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Fgf17 protein (Rattus norvegicus) - STRING interaction network
"Fgf17" - Fibroblast growth factor 17 in Rattus norvegicus
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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Fgf17Fibroblast growth factor 17; Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development (216 aa)    
Predicted Functional Partners:
Fgfr2
Fibroblast growth factor receptor 2 (841 aa)
       
  0.981
Fgfr1
Fibroblast growth factor receptor 1; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 lea [...] (822 aa)
     
  0.979
Fgfr4
Fibroblast growth factor receptor 4; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of [...] (800 aa)
     
  0.969
Fgfr3
Fibroblast growth factor receptor 3 (800 aa)
     
  0.969
Fgf3
Fibroblast growth factor 3; Belongs to the heparin-binding growth factors family (245 aa)
     
 
  0.960
Fgf19
Fibroblast growth factor 19; Belongs to the heparin-binding growth factors family (218 aa)
         
  0.958
Fgf5
Fibroblast growth factor 5; Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase (By similarity); Belongs to the heparin-binding growth factors family (266 aa)
         
  0.956
Fgf23
Fibroblast growth factor 23; Regulator of phosphate homeostasis (By similarity). Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (By similarity). Regulator of vitamin-D metabolism (By similarity). Negatively regulates osteoblasts differentiation and matrix mineralization (By similarity). Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL; Belongs to the heparin-binding growth factors family (251 aa)
         
  0.949
Fgfrl1
Fibroblast growth factor receptor-like 1; Has a negative effect on cell proliferation (529 aa)
       
  0.942
Frs2
Fibroblast growth factor receptor substrate 2 (508 aa)
         
  0.935
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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