Myl1 protein (Rattus norvegicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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proteins of unknown 3D structure

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Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Myh1	Myh3	ENSRNOP00000004295	ENSRNOP00000004147	Myosin-4; Muscle contraction.	Myosin-3; Muscle contraction.	0.948
Myh1	Myh6	ENSRNOP00000004295	ENSRNOP00000023301	Myosin-4; Muscle contraction.	Myosin-6; Muscle contraction.	0.907
Myh1	Myh7	ENSRNOP00000004295	ENSRNOP00000024186	Myosin-4; Muscle contraction.	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.915
Myh1	Myh7b	ENSRNOP00000004295	ENSRNOP00000025859	Myosin-4; Muscle contraction.	Myosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.916
Myh1	Myl1	ENSRNOP00000004295	ENSRNOP00000017838	Myosin-4; Muscle contraction.	Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.	0.994
Myh1	Myl2	ENSRNOP00000004295	ENSRNOP00000039707	Myosin-4; Muscle contraction.	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...]	0.904
Myh1	Myl3	ENSRNOP00000004295	ENSRNOP00000028458	Myosin-4; Muscle contraction.	Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium.	0.993
Myh1	Myl4	ENSRNOP00000004295	ENSRNOP00000064224	Myosin-4; Muscle contraction.	Myosin light chain 4; Regulatory light chain of myosin. Does not bind calcium.	0.989
Myh1	Mylpf	ENSRNOP00000004295	ENSRNOP00000023944	Myosin-4; Muscle contraction.	Myosin regulatory light chain 2, skeletal muscle isoform.	0.929
Myh1	Tnnt3	ENSRNOP00000004295	ENSRNOP00000049386	Myosin-4; Muscle contraction.	Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.838
Myh3	Myh1	ENSRNOP00000004147	ENSRNOP00000004295	Myosin-3; Muscle contraction.	Myosin-4; Muscle contraction.	0.948
Myh3	Myh6	ENSRNOP00000004147	ENSRNOP00000023301	Myosin-3; Muscle contraction.	Myosin-6; Muscle contraction.	0.939
Myh3	Myh7	ENSRNOP00000004147	ENSRNOP00000024186	Myosin-3; Muscle contraction.	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.945
Myh3	Myh7b	ENSRNOP00000004147	ENSRNOP00000025859	Myosin-3; Muscle contraction.	Myosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.994
Myh3	Myl1	ENSRNOP00000004147	ENSRNOP00000017838	Myosin-3; Muscle contraction.	Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.	0.987
Myh3	Myl2	ENSRNOP00000004147	ENSRNOP00000039707	Myosin-3; Muscle contraction.	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...]	0.917
Myh3	Myl3	ENSRNOP00000004147	ENSRNOP00000028458	Myosin-3; Muscle contraction.	Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium.	0.982
Myh3	Myl4	ENSRNOP00000004147	ENSRNOP00000064224	Myosin-3; Muscle contraction.	Myosin light chain 4; Regulatory light chain of myosin. Does not bind calcium.	0.989
Myh3	Mylpf	ENSRNOP00000004147	ENSRNOP00000023944	Myosin-3; Muscle contraction.	Myosin regulatory light chain 2, skeletal muscle isoform.	0.817
Myh3	Tnnt3	ENSRNOP00000004147	ENSRNOP00000049386	Myosin-3; Muscle contraction.	Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.864

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