node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cldn19 | Cnnm2 | ENSRNOP00000050261 | ENSRNOP00000051583 | Claudin-19; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. | Metal transporter CNNM2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+). | 0.449 |
Cldn19 | Slc41a1 | ENSRNOP00000050261 | ENSRNOP00000060385 | Claudin-19; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. | Solute carrier family 41 member 1. | 0.583 |
Cldn19 | Slc41a2 | ENSRNOP00000050261 | ENSRNOP00000011572 | Claudin-19; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. | Solute carrier family 41, member 2 (Predicted). | 0.427 |
Cldn19 | Slc41a3 | ENSRNOP00000050261 | ENSRNOP00000071826 | Claudin-19; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. | Solute carrier family 41 member 3. | 0.505 |
Cldn19 | Trpm6 | ENSRNOP00000050261 | ENSRNOP00000017892 | Claudin-19; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. | Transient receptor potential cation channel, subfamily M, member 6. | 0.819 |
Cldn19 | Trpm7 | ENSRNOP00000050261 | ENSRNOP00000070727 | Claudin-19; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. | Transient receptor potential cation channel subfamily M member 7; Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A [...] | 0.452 |
Cldn19 | Trpv5 | ENSRNOP00000050261 | ENSRNOP00000020975 | Claudin-19; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. | Transient receptor potential cation channel subfamily V member 5; Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification (By similarity). A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay (By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. [...] | 0.531 |
Cnnm1 | Slc41a1 | ENSRNOP00000021876 | ENSRNOP00000060385 | Cyclin and CBS domain divalent metal cation transport mediator 1. | Solute carrier family 41 member 1. | 0.684 |
Cnnm1 | Slc41a2 | ENSRNOP00000021876 | ENSRNOP00000011572 | Cyclin and CBS domain divalent metal cation transport mediator 1. | Solute carrier family 41, member 2 (Predicted). | 0.701 |
Cnnm1 | Slc41a3 | ENSRNOP00000021876 | ENSRNOP00000071826 | Cyclin and CBS domain divalent metal cation transport mediator 1. | Solute carrier family 41 member 3. | 0.592 |
Cnnm1 | Trpm6 | ENSRNOP00000021876 | ENSRNOP00000017892 | Cyclin and CBS domain divalent metal cation transport mediator 1. | Transient receptor potential cation channel, subfamily M, member 6. | 0.745 |
Cnnm1 | Trpm7 | ENSRNOP00000021876 | ENSRNOP00000070727 | Cyclin and CBS domain divalent metal cation transport mediator 1. | Transient receptor potential cation channel subfamily M member 7; Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A [...] | 0.642 |
Cnnm2 | Cldn19 | ENSRNOP00000051583 | ENSRNOP00000050261 | Metal transporter CNNM2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+). | Claudin-19; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. | 0.449 |
Cnnm2 | Slc41a1 | ENSRNOP00000051583 | ENSRNOP00000060385 | Metal transporter CNNM2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+). | Solute carrier family 41 member 1. | 0.788 |
Cnnm2 | Slc41a2 | ENSRNOP00000051583 | ENSRNOP00000011572 | Metal transporter CNNM2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+). | Solute carrier family 41, member 2 (Predicted). | 0.709 |
Cnnm2 | Slc41a3 | ENSRNOP00000051583 | ENSRNOP00000071826 | Metal transporter CNNM2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+). | Solute carrier family 41 member 3. | 0.707 |
Cnnm2 | Trpm6 | ENSRNOP00000051583 | ENSRNOP00000017892 | Metal transporter CNNM2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+). | Transient receptor potential cation channel, subfamily M, member 6. | 0.747 |
Cnnm2 | Trpm7 | ENSRNOP00000051583 | ENSRNOP00000070727 | Metal transporter CNNM2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+). | Transient receptor potential cation channel subfamily M member 7; Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A [...] | 0.669 |
Slc41a1 | Cldn19 | ENSRNOP00000060385 | ENSRNOP00000050261 | Solute carrier family 41 member 1. | Claudin-19; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. | 0.583 |
Slc41a1 | Cnnm1 | ENSRNOP00000060385 | ENSRNOP00000021876 | Solute carrier family 41 member 1. | Cyclin and CBS domain divalent metal cation transport mediator 1. | 0.684 |