Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Birc2 | Birc3 | ENSRNOP00000014560 | ENSRNOP00000007702 | Baculoviral IAP repeat-containing 2. | Baculoviral IAP repeat-containing 3. | 0.983 |
| Birc2 | Ikbkg | ENSRNOP00000014560 | ENSRNOP00000075158 | Baculoviral IAP repeat-containing 2. | NF-kappa-B essential modulator; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. Also considered to be a mediator for TAX activation of NF- kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral [...] | 0.909 |
| Birc2 | Rbck1 | ENSRNOP00000014560 | ENSRNOP00000072645 | Baculoviral IAP repeat-containing 2. | RanBP-type and C3HC4-type zinc finger-containing protein 1; Component of the LUBAC complex which conjugates linear ('Met- 1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF- induced cell death and thereby prevents inflammation. LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC) following p [...] | 0.968 |
| Birc2 | Ripk1 | ENSRNOP00000014560 | ENSRNOP00000023962 | Baculoviral IAP repeat-containing 2. | Receptor (TNFRSF)-interacting serine-threonine kinase 1 (Predicted). | 0.994 |
| Birc2 | Rnf31 | ENSRNOP00000014560 | ENSRNOP00000026333 | Baculoviral IAP repeat-containing 2. | Ring finger protein 31 (Predicted), isoform CRA_a. | 0.983 |
| Birc2 | Sharpin | ENSRNOP00000014560 | ENSRNOP00000018032 | Baculoviral IAP repeat-containing 2. | Sharpin; Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BI [...] | 0.969 |
| Birc2 | Tnfrsf1a | ENSRNOP00000014560 | ENSRNOP00000042371 | Baculoviral IAP repeat-containing 2. | Tumor necrosis factor receptor superfamily member 1A; Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity). | 0.979 |
| Birc2 | Traf2 | ENSRNOP00000014560 | ENSRNOP00000008253 | Baculoviral IAP repeat-containing 2. | TNF receptor-associated factor. | 0.997 |
| Birc3 | Birc2 | ENSRNOP00000007702 | ENSRNOP00000014560 | Baculoviral IAP repeat-containing 3. | Baculoviral IAP repeat-containing 2. | 0.983 |
| Birc3 | Ikbkg | ENSRNOP00000007702 | ENSRNOP00000075158 | Baculoviral IAP repeat-containing 3. | NF-kappa-B essential modulator; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. Also considered to be a mediator for TAX activation of NF- kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral [...] | 0.910 |
| Birc3 | Rbck1 | ENSRNOP00000007702 | ENSRNOP00000072645 | Baculoviral IAP repeat-containing 3. | RanBP-type and C3HC4-type zinc finger-containing protein 1; Component of the LUBAC complex which conjugates linear ('Met- 1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF- induced cell death and thereby prevents inflammation. LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC) following p [...] | 0.970 |
| Birc3 | Ripk1 | ENSRNOP00000007702 | ENSRNOP00000023962 | Baculoviral IAP repeat-containing 3. | Receptor (TNFRSF)-interacting serine-threonine kinase 1 (Predicted). | 0.994 |
| Birc3 | Rnf31 | ENSRNOP00000007702 | ENSRNOP00000026333 | Baculoviral IAP repeat-containing 3. | Ring finger protein 31 (Predicted), isoform CRA_a. | 0.983 |
| Birc3 | Sharpin | ENSRNOP00000007702 | ENSRNOP00000018032 | Baculoviral IAP repeat-containing 3. | Sharpin; Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BI [...] | 0.970 |
| Birc3 | Tnfrsf1a | ENSRNOP00000007702 | ENSRNOP00000042371 | Baculoviral IAP repeat-containing 3. | Tumor necrosis factor receptor superfamily member 1A; Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity). | 0.989 |
| Birc3 | Traf2 | ENSRNOP00000007702 | ENSRNOP00000008253 | Baculoviral IAP repeat-containing 3. | TNF receptor-associated factor. | 0.998 |
| Ikbkg | Birc2 | ENSRNOP00000075158 | ENSRNOP00000014560 | NF-kappa-B essential modulator; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. Also considered to be a mediator for TAX activation of NF- kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral [...] | Baculoviral IAP repeat-containing 2. | 0.909 |
| Ikbkg | Birc3 | ENSRNOP00000075158 | ENSRNOP00000007702 | NF-kappa-B essential modulator; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. Also considered to be a mediator for TAX activation of NF- kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral [...] | Baculoviral IAP repeat-containing 3. | 0.910 |
| Ikbkg | Otulin | ENSRNOP00000075158 | ENSRNOP00000016111 | NF-kappa-B essential modulator; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. Also considered to be a mediator for TAX activation of NF- kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral [...] | OTU deubiquitinase with linear linkage-specificity. | 0.464 |
| Ikbkg | Rbck1 | ENSRNOP00000075158 | ENSRNOP00000072645 | NF-kappa-B essential modulator; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. Also considered to be a mediator for TAX activation of NF- kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral [...] | RanBP-type and C3HC4-type zinc finger-containing protein 1; Component of the LUBAC complex which conjugates linear ('Met- 1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF- induced cell death and thereby prevents inflammation. LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC) following p [...] | 0.991 |
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