node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Agbl2 | Cpa4 | ENSRNOP00000011467 | ENSRNOP00000013880 | ATP/GTP-binding protein-like 2. | Similar to carboxypeptidase A4 (Predicted). | 0.600 |
Agbl2 | Lxn | ENSRNOP00000011467 | ENSRNOP00000018402 | ATP/GTP-binding protein-like 2. | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | 0.661 |
Cpa1 | Cpa2 | ENSRNOP00000014465 | ENSRNOP00000038495 | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. | Carboxypeptidase A2. | 0.953 |
Cpa1 | Lxn | ENSRNOP00000014465 | ENSRNOP00000018402 | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | 0.712 |
Cpa2 | Cpa1 | ENSRNOP00000038495 | ENSRNOP00000014465 | Carboxypeptidase A2. | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. | 0.953 |
Cpa2 | Lxn | ENSRNOP00000038495 | ENSRNOP00000018402 | Carboxypeptidase A2. | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | 0.732 |
Cpa4 | Agbl2 | ENSRNOP00000013880 | ENSRNOP00000011467 | Similar to carboxypeptidase A4 (Predicted). | ATP/GTP-binding protein-like 2. | 0.600 |
Cpa4 | Lxn | ENSRNOP00000013880 | ENSRNOP00000018402 | Similar to carboxypeptidase A4 (Predicted). | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | 0.807 |
Gng2 | Lxn | ENSRNOP00000066927 | ENSRNOP00000018402 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | 0.516 |
Gng2 | Ntng2 | ENSRNOP00000066927 | ENSRNOP00000045926 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Netrin G2 (Predicted), isoform CRA_a. | 0.583 |
Lxn | Agbl2 | ENSRNOP00000018402 | ENSRNOP00000011467 | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | ATP/GTP-binding protein-like 2. | 0.661 |
Lxn | Cpa1 | ENSRNOP00000018402 | ENSRNOP00000014465 | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. | 0.712 |
Lxn | Cpa2 | ENSRNOP00000018402 | ENSRNOP00000038495 | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | Carboxypeptidase A2. | 0.732 |
Lxn | Cpa4 | ENSRNOP00000018402 | ENSRNOP00000013880 | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | Similar to carboxypeptidase A4 (Predicted). | 0.807 |
Lxn | Gng2 | ENSRNOP00000018402 | ENSRNOP00000066927 | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.516 |
Lxn | Npsr1 | ENSRNOP00000018402 | ENSRNOP00000021625 | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | 0.508 |
Lxn | Ntng2 | ENSRNOP00000018402 | ENSRNOP00000045926 | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | Netrin G2 (Predicted), isoform CRA_a. | 0.748 |
Lxn | Tesc | ENSRNOP00000018402 | ENSRNOP00000001490 | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | Tescalcin. | 0.578 |
Lxn | Timp3 | ENSRNOP00000018402 | ENSRNOP00000005746 | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | Metalloproteinase inhibitor 3; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. | 0.551 |
Lxn | Tm7sf3 | ENSRNOP00000018402 | ENSRNOP00000002486 | Latexin; Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity). Belongs to the protease inhibitor I47 (latexin) family. | Transmembrane 7 superfamily member 3; Involved in the inhibition of cytokine-induced death of pancreatic beta cells (By similarity). Involved in the promotion of insulin secretion from pancreatic beta cells (By similarity). Is a downstream transcriptional target of p53/TP53, and acts as a pro- survival homeostatic factor that attenuates the development of cellular stress. Maintains protein homeostasis and promotes cell survival through attenuation of endoplasmic reticulum (ER) stress and the subsequent induction of unfolded protein response (UPR) (By similarity). | 0.557 |