STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ankrd10Ankyrin repeat domain 10. (415 aa)    
Predicted Functional Partners:
Sugp2
Splicing factor, arginine/serine-rich 14 (Predicted).
   
  
 0.616
Fcf1
Similar to CGI-35 protein (Predicted), isoform CRA_a.
   
  
 0.605
Rrp8
Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...]
   
 
 0.579
Dleu7
Deleted in lymphocytic leukemia, 7 (Predicted), isoform CRA_b.
      
 0.551
Mmachc
Methylmalonic aciduria (Cobalamin deficiency) cblC type, with homocystinuria (Predicted).
   
 
 0.547
Syap1
Synapse associated protein 1, isoform CRA_a.
   
  
 0.543
Commd9
COMM domain containing 9, isoform CRA_a.
   
 
 0.527
Nol7
Nucleolar protein 7.
      
 0.503
Pms1
PMS1 homolog 1, mismatch repair system component.
   
  
 0.498
Enox1
Ecto-NOX disulfide-thiol exchanger 1.
      
 0.489
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.