node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atox1 | Atp7a | ENSRNOP00000017588 | ENSRNOP00000073176 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells (By similarity). | 0.997 |
Atox1 | Atp7b | ENSRNOP00000017588 | ENSRNOP00000069905 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile. | 0.991 |
Atox1 | Ccs | ENSRNOP00000017588 | ENSRNOP00000065189 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family. | 0.943 |
Atox1 | Cox17 | ENSRNOP00000017588 | ENSRNOP00000056297 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | Cytochrome C oxidase assembly protein COX17. | 0.958 |
Atox1 | Slc31a2 | ENSRNOP00000017588 | ENSRNOP00000019379 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | Solute carrier family 31, member 2, isoform CRA_a. | 0.623 |
Atp7a | Atox1 | ENSRNOP00000073176 | ENSRNOP00000017588 | Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells (By similarity). | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | 0.997 |
Atp7a | Atp7b | ENSRNOP00000073176 | ENSRNOP00000069905 | Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells (By similarity). | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile. | 0.906 |
Atp7a | Ccs | ENSRNOP00000073176 | ENSRNOP00000065189 | Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells (By similarity). | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family. | 0.990 |
Atp7a | Cox17 | ENSRNOP00000073176 | ENSRNOP00000056297 | Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells (By similarity). | Cytochrome C oxidase assembly protein COX17. | 0.870 |
Atp7a | Slc31a2 | ENSRNOP00000073176 | ENSRNOP00000019379 | Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells (By similarity). | Solute carrier family 31, member 2, isoform CRA_a. | 0.638 |
Atp7b | Atox1 | ENSRNOP00000069905 | ENSRNOP00000017588 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile. | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | 0.991 |
Atp7b | Atp7a | ENSRNOP00000069905 | ENSRNOP00000073176 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile. | Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells (By similarity). | 0.906 |
Atp7b | Ccs | ENSRNOP00000069905 | ENSRNOP00000065189 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile. | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family. | 0.987 |
Atp7b | Cox17 | ENSRNOP00000069905 | ENSRNOP00000056297 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile. | Cytochrome C oxidase assembly protein COX17. | 0.819 |
Atp7b | Slc31a2 | ENSRNOP00000069905 | ENSRNOP00000019379 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile. | Solute carrier family 31, member 2, isoform CRA_a. | 0.701 |
Bspry | Cdc26 | ENSRNOP00000020366 | ENSRNOP00000049754 | B box and SPRY domain-containing protein; May regulate epithelial calcium transport by inhibiting TRPV5 activity. | Anaphase-promoting complex subunit CDC26; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex (By similarity); Belongs to the CDC26 [...] | 0.563 |
Bspry | Nif3l1 | ENSRNOP00000020366 | ENSRNOP00000018014 | B box and SPRY domain-containing protein; May regulate epithelial calcium transport by inhibiting TRPV5 activity. | NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation. | 0.591 |
Bspry | Slc31a2 | ENSRNOP00000020366 | ENSRNOP00000019379 | B box and SPRY domain-containing protein; May regulate epithelial calcium transport by inhibiting TRPV5 activity. | Solute carrier family 31, member 2, isoform CRA_a. | 0.615 |
Ccs | Atox1 | ENSRNOP00000065189 | ENSRNOP00000017588 | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family. | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | 0.943 |
Ccs | Atp7a | ENSRNOP00000065189 | ENSRNOP00000073176 | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family. | Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells (By similarity). | 0.990 |