Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Dhfr | Ftcd | ENSRNOP00000018259 | ENSRNOP00000001699 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA (By similarity). | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | 0.953 |
| Dhfr | Gart | ENSRNOP00000018259 | ENSRNOP00000033253 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA (By similarity). | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.982 |
| Dhfr | LOC680432 | ENSRNOP00000018259 | ENSRNOP00000023913 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA (By similarity). | Uncharacterized protein. | 0.974 |
| Dhfr | Mtfmt | ENSRNOP00000018259 | ENSRNOP00000019671 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA (By similarity). | Methionyl-tRNA formyltransferase, mitochondrial; Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism (By similarity); Belongs to the Fmt family. | 0.976 |
| Dhfr | Mthfd1 | ENSRNOP00000018259 | ENSRNOP00000008374 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA (By similarity). | C-1-tetrahydrofolate synthase, cytoplasmic; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | 0.985 |
| Dhfr | Mthfd2 | ENSRNOP00000018259 | ENSRNOP00000014603 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA (By similarity). | RCG56426. | 0.780 |
| Dhfr | Mthfd2l | ENSRNOP00000018259 | ENSRNOP00000044342 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA (By similarity). | Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2; Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family. | 0.763 |
| Dhfr | Mtr | ENSRNOP00000018259 | ENSRNOP00000023973 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA (By similarity). | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). | 0.979 |
| Dhfr | Shmt1 | ENSRNOP00000018259 | ENSRNOP00000007092 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA (By similarity). | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.994 |
| Dhfr | Shmt2 | ENSRNOP00000018259 | ENSRNOP00000011082 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA (By similarity). | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.992 |
| Ftcd | Dhfr | ENSRNOP00000001699 | ENSRNOP00000018259 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA (By similarity). | 0.953 |
| Ftcd | Gart | ENSRNOP00000001699 | ENSRNOP00000033253 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.992 |
| Ftcd | LOC680432 | ENSRNOP00000001699 | ENSRNOP00000023913 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | Uncharacterized protein. | 0.969 |
| Ftcd | Mtfmt | ENSRNOP00000001699 | ENSRNOP00000019671 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | Methionyl-tRNA formyltransferase, mitochondrial; Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism (By similarity); Belongs to the Fmt family. | 0.957 |
| Ftcd | Mthfd1 | ENSRNOP00000001699 | ENSRNOP00000008374 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | C-1-tetrahydrofolate synthase, cytoplasmic; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | 0.984 |
| Ftcd | Mthfd2 | ENSRNOP00000001699 | ENSRNOP00000014603 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | RCG56426. | 0.981 |
| Ftcd | Mthfd2l | ENSRNOP00000001699 | ENSRNOP00000044342 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2; Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family. | 0.979 |
| Ftcd | Mtr | ENSRNOP00000001699 | ENSRNOP00000023973 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). | 0.938 |
| Ftcd | Shmt1 | ENSRNOP00000001699 | ENSRNOP00000007092 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.959 |
| Ftcd | Shmt2 | ENSRNOP00000001699 | ENSRNOP00000011082 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.947 |
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