STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Wfdc2WAP four-disulfide core domain protein 2; Broad range protease inhibitor. (168 aa)    
Predicted Functional Partners:
Eddm3b
Epididymal protein 3B.
      
 0.781
Ly6g5c
Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation.
      
 0.693
Adgrg2
Adhesion G-protein coupled receptor G2; Orphan receptor. Could be involved in a signal transduction pathway controlling epididymal function and male fertility. May regulate fluid exchange within epididymis.
    
 
 0.660
Wap
Whey acidic protein; Could be a protease inhibitor.
    
 
 0.659
Npc2
NPC intracellular cholesterol transporter 2.
   
  
 0.605
Wfdc3
WAP four-disulfide core domain 3 (Predicted), isoform CRA_a.
  
 
 0.564
Wfdc11
WAP four-disulfide core domain protein 11.
      
 0.537
Prb1
Proline-rich protein BstNI subfamily 1.
   
 
 0.504
Wfdc9
Protein WFDC9.
      
 0.493
Bpifb2
Bactericidal/permeability-increasing protein-like 1 (Predicted).
   
  
 0.485
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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