Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Atxn10Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Belongs to the ataxin-10 family. (475 aa)    
Predicted Functional Partners:
Atxn2
Ataxin 2.
   
  
 0.674
Tgm6
Transglutaminase 6.
   
  
 0.647
Abce1
ATP-binding cassette, sub-family E (OABP), member 1.
    
   0.636
Iqcb1
IQ calmodulin-binding motif containing 1 (Predicted), isoform CRA_a.
    
 
 0.634
Sacs
Sacsin molecular chaperone.
      
 0.604
Egfr
Receptor protein-tyrosine kinase.
    
 
 0.593
Hypk
Huntingtin-interacting protein K.
   
  
 0.591
Tnni3
Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
   
  
 0.591
Sptbn2
Spectrin beta chain, non-erythrocytic 2; Probably plays an important role in neuronal membrane skeleton.
   
  
 0.587
Bean1
Brain-expressed,-associated with NEDD4, 1.
      
 0.571
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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