Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Abcc12Multidrug resistance-associated protein 9; Probable transporter. (1366 aa)    
Predicted Functional Partners:
Abcf2
ATP-binding cassette subfamily F member 2.
   
 0.673
Slc10a1
Sodium/bile acid cotransporter; The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.
      
 0.542
Abca12
ATP-binding cassette subfamily A member 12.
   
0.504
Abcc6
Multidrug resistance-associated protein 6; May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly.
     
0.500
Suox
Sulfite oxidase, mitochondrial.
     
 0.499
N4bp1
Nedd4-binding protein 1.
      
 0.485
Abcc3
Canalicular multispecific organic anion transporter 2; May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity).
     
0.481
Abcg1
ATP-binding cassette, sub-family G (WHITE), member 1, isoform CRA_a.
    
 0.474
Abce1
ATP-binding cassette, sub-family E (OABP), member 1.
      
 0.474
Abca13
ATP-binding cassette subfamily A member 13.
   
0.469
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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