Slc2a13 protein (Rattus norvegicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Frmpd1	Slc2a13	ENSRNOP00000016839	ENSRNOP00000021153	FERM and PDZ domain-containing 1.	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	0.491
Frmpd1	Spats2l	ENSRNOP00000016839	ENSRNOP00000069610	FERM and PDZ domain-containing 1.	SPATS2-like protein.	0.501
Frmpd1	Tmem51	ENSRNOP00000016839	ENSRNOP00000019171	FERM and PDZ domain-containing 1.	Similar to BC003277 protein (Predicted), isoform CRA_a.	0.505
Impa1	Isyna1	ENSRNOP00000014274	ENSRNOP00000026821	Inositol monophosphatase 1; Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol 1,3- diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta- glycerophosphate, and 2'-AMP as substrates (By similarity). Is equally active with myo-inositol monophosphate and D-galactose 1-phosphate.	Inositol-3-phosphate synthase 1; Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1- phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds (By similarity).	0.977
Impa1	Slc2a13	ENSRNOP00000014274	ENSRNOP00000021153	Inositol monophosphatase 1; Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol 1,3- diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta- glycerophosphate, and 2'-AMP as substrates (By similarity). Is equally active with myo-inositol monophosphate and D-galactose 1-phosphate.	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	0.501
Isyna1	Impa1	ENSRNOP00000026821	ENSRNOP00000014274	Inositol-3-phosphate synthase 1; Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1- phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds (By similarity).	Inositol monophosphatase 1; Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol 1,3- diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta- glycerophosphate, and 2'-AMP as substrates (By similarity). Is equally active with myo-inositol monophosphate and D-galactose 1-phosphate.	0.977
Isyna1	Slc2a13	ENSRNOP00000026821	ENSRNOP00000021153	Inositol-3-phosphate synthase 1; Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1- phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds (By similarity).	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	0.523
Slc22a12	Slc2a13	ENSRNOP00000028665	ENSRNOP00000021153	Solute carrier family 22 member 12; Required for efficient urate re-absorption in the kidney. Regulates blood urate levels. Mediates saturable urate uptake by facilitating the exchange of urate against organic anions or chloride ions (By similarity).	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	0.504
Slc2a13	Frmpd1	ENSRNOP00000021153	ENSRNOP00000016839	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	FERM and PDZ domain-containing 1.	0.491
Slc2a13	Impa1	ENSRNOP00000021153	ENSRNOP00000014274	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	Inositol monophosphatase 1; Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol 1,3- diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta- glycerophosphate, and 2'-AMP as substrates (By similarity). Is equally active with myo-inositol monophosphate and D-galactose 1-phosphate.	0.501
Slc2a13	Isyna1	ENSRNOP00000021153	ENSRNOP00000026821	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	Inositol-3-phosphate synthase 1; Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1- phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds (By similarity).	0.523
Slc2a13	Slc22a12	ENSRNOP00000021153	ENSRNOP00000028665	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	Solute carrier family 22 member 12; Required for efficient urate re-absorption in the kidney. Regulates blood urate levels. Mediates saturable urate uptake by facilitating the exchange of urate against organic anions or chloride ions (By similarity).	0.504
Slc2a13	Slc5a11	ENSRNOP00000021153	ENSRNOP00000073553	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	Sodium/myo-inositol cotransporter 2; Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D- chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney.	0.554
Slc2a13	Spats2l	ENSRNOP00000021153	ENSRNOP00000069610	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	SPATS2-like protein.	0.498
Slc2a13	Swt1	ENSRNOP00000021153	ENSRNOP00000049813	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	Similar to RIKEN cDNA 1200016B10 (Predicted), isoform CRA_a.	0.531
Slc2a13	Tmem117	ENSRNOP00000021153	ENSRNOP00000008159	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	Transmembrane protein 117.	0.592
Slc2a13	Tmem51	ENSRNOP00000021153	ENSRNOP00000019171	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	Similar to BC003277 protein (Predicted), isoform CRA_a.	0.491
Slc2a13	Zcrb1	ENSRNOP00000021153	ENSRNOP00000006780	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	Zinc finger CCHC-type and RNA-binding motif-containing protein 1.	0.503
Slc5a11	Slc2a13	ENSRNOP00000073553	ENSRNOP00000021153	Sodium/myo-inositol cotransporter 2; Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D- chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney.	Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.	0.554
Spats2l	Frmpd1	ENSRNOP00000069610	ENSRNOP00000016839	SPATS2-like protein.	FERM and PDZ domain-containing 1.	0.501

page 1 of 2

Server load: low (14%) [HD]

Share

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About