Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cbwd1COBW domain-containing protein 1; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily. (394 aa)    
Predicted Functional Partners:
Metap1
Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
   
 
 0.813
Fam72a
Protein FAM72A; May play a role in the regulation of cellular reactive oxygen species metabolism. May participate in cell growth regulation (By similarity); Belongs to the FAM72 family.
      
 0.735
Tcerg1
Transcription elongation regulator 1.
   
 
 0.728
Mrpl33
Brain and reproductive organ-expressed protein, isoform CRA_c.
  
  
 0.639
Rps29
40S ribosomal protein S29.
  
 
 0.588
ENSRNOP00000040703
40S ribosomal protein S29.
  
 
 0.588
ENSRNOP00000043270
40S ribosomal protein S29.
  
 
 0.588
LOC108350501
Ribosomal protein S29.
  
 
 0.588
Mrps14
Mitochondrial ribosomal protein S14 (Predicted), isoform CRA_b.
  
 
 0.582
Nvl
Nuclear VCP-like (Predicted).
   
  
 0.567
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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