STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PipProlactin-inducible protein homolog; Belongs to the PIP family. (146 aa)    
Predicted Functional Partners:
Azgp1
Zinc-alpha-2-glycoprotein; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. Belongs to the MHC class I family.
   
 0.981
Csap1
Common salivary protein 1.
   
  
 0.824
Grpca
Submandibular gland secretory Glx-rich protein CB; GRP proteins have a marked affinity for hydroxyapatite. They may play a role in the formation of the protective acquired pellicle at the saliva-tooth interface.
   
  
 0.756
Bpifa2
BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
   
  
 0.750
Armh4
Armadillo-like helical domain-containing 4.
   
  
 0.658
P22k15
Cystatin-related protein 2; Belongs to the cystatin family.
   
  
 0.655
RGD1306750
Gliadoralin-A; May play a role in the formation of the protective mucosal protein pellicle involved in the reinforcement and protection of oral mucosal epithelial surface.
      
 0.611
Oprpn
Opiorphin prepropeptide.
   
  
 0.579
Tsacc
Similar to SSTK-interacting protein (Predicted), isoform CRA_a.
      
 0.568
Zp3
Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
  
  
 0.567
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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