Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Npsr1Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. (371 aa)    
Predicted Functional Partners:
Nps
Neuropeptide S; May play an important anorexigenic role. Modulates arousal and anxiety as well as increases locomotor activity. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations.
     
 0.998
D3ZGS7_RAT
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 
 0.905
Fau
Ubiquitin-like protein FUBI.
   
 
 0.905
LOC687780
Ubiquitin-like protein fubi and ribosomal protein S30-like.
   
 
 0.905
LOC687780-2
FAU, ubiquitin like and ribosomal protein S30 fusion.
   
 
 0.905
Eef1g
Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.
   
 
 0.887
Rpl4
60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.
  
 
 0.857
Rpl23
60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.848
Rpl18
60S ribosomal protein L18; Component of the large ribosomal subunit.
  
 
 0.847
Rsl24d1
Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity).
   
 
 0.841
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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