STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gpr162G protein-coupled receptor 162 (Predicted). (588 aa)    
Predicted Functional Partners:
Gpr152
G protein-coupled receptor 152; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.688
Tmem221
Transmembrane protein 221.
      
 0.627
Gpr26
G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP (By similarity).
   
  
 0.617
Gpr137c
G protein-coupled receptor 137C.
   
  
 0.595
Tmem211
Transmembrane protein 211.
   
  
 0.584
Gpr22
G-protein coupled receptor 22; Orphan G-protein coupled receptor. Seems to act through a G(i)/G(o) mediated pathway (By similarity). May be involved in ciliogenesis (By similarity).
   
  
 0.580
Rnf227
Similar to RIKEN cDNA A030009H04.
   
 
 0.575
Tmem191c
Transmembrane protein 191C.
      
 0.571
Gpr82
G protein-coupled receptor 82.
      
 0.571
Gpr146
G protein-coupled receptor 146.
   
  
 0.570
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.