node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Asf1a | Asf1b | ENSRNOP00000000471 | ENSRNOP00000006964 | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) (Predicted), isoform CRA_a. | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) (Predicted). | 0.629 |
Asf1a | Hat1 | ENSRNOP00000000471 | ENSRNOP00000002085 | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) (Predicted), isoform CRA_a. | Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes; Belongs to the HAT1 family. | 0.883 |
Asf1a | Mcm6 | ENSRNOP00000000471 | ENSRNOP00000004969 | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) (Predicted), isoform CRA_a. | DNA replication licensing factor MCM6; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.630 |
Asf1a | Mcm7 | ENSRNOP00000000471 | ENSRNOP00000001825 | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) (Predicted), isoform CRA_a. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.570 |
Asf1a | Nasp | ENSRNOP00000000471 | ENSRNOP00000022170 | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) (Predicted), isoform CRA_a. | Nuclear autoantigenic sperm protein; Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA. | 0.946 |
Asf1a | RGD1563620 | ENSRNOP00000000471 | ENSRNOP00000033725 | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) (Predicted), isoform CRA_a. | Similar to retinoblastoma-binding protein 4. | 0.647 |
Asf1a | Rbbp4 | ENSRNOP00000000471 | ENSRNOP00000036568 | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) (Predicted), isoform CRA_a. | RB-binding protein 4, chromatin-remodeling factor. | 0.681 |
Asf1a | Rbbp7 | ENSRNOP00000000471 | ENSRNOP00000062148 | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) (Predicted), isoform CRA_a. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and [...] | 0.811 |
Asf1a | Wdr73 | ENSRNOP00000000471 | ENSRNOP00000029102 | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) (Predicted), isoform CRA_a. | Neuromedin B (Predicted), isoform CRA_d. | 0.587 |
Asf1b | Asf1a | ENSRNOP00000006964 | ENSRNOP00000000471 | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) (Predicted). | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) (Predicted), isoform CRA_a. | 0.629 |
Asf1b | Hat1 | ENSRNOP00000006964 | ENSRNOP00000002085 | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) (Predicted). | Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes; Belongs to the HAT1 family. | 0.867 |
Asf1b | Mcm6 | ENSRNOP00000006964 | ENSRNOP00000004969 | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) (Predicted). | DNA replication licensing factor MCM6; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.795 |
Asf1b | Mcm7 | ENSRNOP00000006964 | ENSRNOP00000001825 | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) (Predicted). | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.683 |
Asf1b | Nasp | ENSRNOP00000006964 | ENSRNOP00000022170 | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) (Predicted). | Nuclear autoantigenic sperm protein; Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA. | 0.951 |
Asf1b | RGD1563620 | ENSRNOP00000006964 | ENSRNOP00000033725 | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) (Predicted). | Similar to retinoblastoma-binding protein 4. | 0.647 |
Asf1b | Rbbp4 | ENSRNOP00000006964 | ENSRNOP00000036568 | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) (Predicted). | RB-binding protein 4, chromatin-remodeling factor. | 0.675 |
Asf1b | Rbbp7 | ENSRNOP00000006964 | ENSRNOP00000062148 | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) (Predicted). | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and [...] | 0.655 |
Asf1b | Wdr73 | ENSRNOP00000006964 | ENSRNOP00000029102 | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) (Predicted). | Neuromedin B (Predicted), isoform CRA_d. | 0.576 |
Hat1 | Asf1a | ENSRNOP00000002085 | ENSRNOP00000000471 | Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes; Belongs to the HAT1 family. | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) (Predicted), isoform CRA_a. | 0.883 |
Hat1 | Asf1b | ENSRNOP00000002085 | ENSRNOP00000006964 | Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes; Belongs to the HAT1 family. | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) (Predicted). | 0.867 |