node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aspm | Birc5 | ENSRNOP00000016797 | ENSRNOP00000065784 | Abnormal spindle microtubule assembly. | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | 0.839 |
Aspm | Bub1b | ENSRNOP00000016797 | ENSRNOP00000010406 | Abnormal spindle microtubule assembly. | BUB1 mitotic checkpoint serine/threonine kinase B. | 0.949 |
Aspm | Ccna2 | ENSRNOP00000016797 | ENSRNOP00000021156 | Abnormal spindle microtubule assembly. | Cyclin A2, isoform CRA_b. | 0.902 |
Aspm | Dlgap5 | ENSRNOP00000016797 | ENSRNOP00000015553 | Abnormal spindle microtubule assembly. | DLG-associated protein 5. | 0.960 |
Aspm | Kif11 | ENSRNOP00000016797 | ENSRNOP00000072698 | Abnormal spindle microtubule assembly. | Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.973 |
Aspm | Nusap1 | ENSRNOP00000016797 | ENSRNOP00000070384 | Abnormal spindle microtubule assembly. | Nucleolar and spindle-associated protein 1. | 0.909 |
Aspm | Pclaf | ENSRNOP00000016797 | ENSRNOP00000022256 | Abnormal spindle microtubule assembly. | PCNA-associated factor; PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork- blocking lesions. Also acts as a regulator of centrosome number (By similarity). | 0.825 |
Aspm | Top2a | ENSRNOP00000016797 | ENSRNOP00000069963 | Abnormal spindle microtubule assembly. | DNA topoisomerase 2-alpha; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. | 0.973 |
Aspm | Ube2c | ENSRNOP00000016797 | ENSRNOP00000020323 | Abnormal spindle microtubule assembly. | Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. | 0.887 |
Birc5 | Aspm | ENSRNOP00000065784 | ENSRNOP00000016797 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Abnormal spindle microtubule assembly. | 0.839 |
Birc5 | Bub1b | ENSRNOP00000065784 | ENSRNOP00000010406 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | BUB1 mitotic checkpoint serine/threonine kinase B. | 0.942 |
Birc5 | Ccna2 | ENSRNOP00000065784 | ENSRNOP00000021156 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Cyclin A2, isoform CRA_b. | 0.939 |
Birc5 | Dlgap5 | ENSRNOP00000065784 | ENSRNOP00000015553 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | DLG-associated protein 5. | 0.943 |
Birc5 | Kif11 | ENSRNOP00000065784 | ENSRNOP00000072698 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.917 |
Birc5 | Nusap1 | ENSRNOP00000065784 | ENSRNOP00000070384 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Nucleolar and spindle-associated protein 1. | 0.951 |
Birc5 | Pclaf | ENSRNOP00000065784 | ENSRNOP00000022256 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | PCNA-associated factor; PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork- blocking lesions. Also acts as a regulator of centrosome number (By similarity). | 0.870 |
Birc5 | Top2a | ENSRNOP00000065784 | ENSRNOP00000069963 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | DNA topoisomerase 2-alpha; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. | 0.963 |
Birc5 | Ube2c | ENSRNOP00000065784 | ENSRNOP00000020323 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. | 0.984 |
Bub1b | Aspm | ENSRNOP00000010406 | ENSRNOP00000016797 | BUB1 mitotic checkpoint serine/threonine kinase B. | Abnormal spindle microtubule assembly. | 0.949 |
Bub1b | Birc5 | ENSRNOP00000010406 | ENSRNOP00000065784 | BUB1 mitotic checkpoint serine/threonine kinase B. | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | 0.942 |