close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nhlrc2NHL repeat containing 2 (Predicted). (725 aa)    
Predicted Functional Partners:
Tm2d3
TM2 domain-containing 3.
      
 0.832
Tm2d2
TM2 domain-containing protein 2.
      
 0.819
Tm2d1
TM2 domain containing 1 (Predicted), isoform CRA_a.
   
  
 0.690
Ccdc186
Coiled-coil domain-containing 186.
   
  
 0.667
Lamtor2
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.
      
 0.654
Lamtor4
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.
      
 0.639
Plekhs1
Similar to RIKEN cDNA 9930023K05 (Predicted).
      
 0.638
Vwa2
Von Willebrand factor A domain-containing 2.
    
 
 0.620
Nprl2
Tumor suppressor candidate 4, isoform CRA_a.
   
 
 0.611
Dclre1a
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae) (Predicted).
   
  
 0.598
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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