STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcn8Lipocalin 8 (Predicted); Belongs to the calycin superfamily. Lipocalin family. (175 aa)    
Predicted Functional Partners:
Lcn9
Lipocalin 9 (Predicted); Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.962
Cst11
Cystatin-11; Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization. Belongs to the cystatin family.
   
  
 0.948
Lcn6
Epididymal-specific lipocalin ELP16; Belongs to the calycin superfamily. Lipocalin family.
  
  
 0.843
Lcn10
Lipocalin 10; Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.753
Obp2b
Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.728
Gpx5
Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
   
  
 0.721
Cst12
Cystatin-12; May play a specialized role in spermatogenesis. Belongs to the cystatin family.
   
  
 0.716
Lcn12
Epididymal-specific lipocalin-12; Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility.
   
  
 0.701
Teddm1
Transmembrane epididymal protein 1.
   
  
 0.673
Cst8
Cystatin-8; Performs a specialized role during sperm development and maturation; Belongs to the cystatin family.
   
  
 0.664
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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