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Mgat3 protein (Rattus norvegicus) - STRING interaction network
"Mgat3" - Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase in Rattus norvegicus
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Mgat3Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase ; It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides (538 aa)    
Predicted Functional Partners:
Mgat4b
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B precursor (548 aa)
         
  0.953
Mgat2
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase ; Catalyzes an essential step in the conversion of oligo- mannose and hybrid to complex N-glycans (442 aa)
     
 
  0.944
Fut8
Alpha-(1,6)-fucosyltransferase ; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (575 aa)
     
 
  0.935
RGD1310572
Glycosyltransferase 54 domain-containing protein (372 aa)
         
    0.900
Cdh1
Cadherin-1 E-Cad/CTF1 E-Cad/CTF2 E-Cad/CTF3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity) (886 aa)
         
  0.681
Ints10
Integrator complex subunit 10 (710 aa)
     
        0.675
Mgat5
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A ; Catalyzes the addition of N-acetylglucosamine in beta 1- 6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides (740 aa)
     
   
  0.634
Mgat4a
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform 1 ; Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells (By similarity) (535 aa)
           
  0.627
Cdh3
Cadherin 3 precursor ; Cadherins are calcium-dependent cell adhesion proteins (822 aa)
         
  0.567
Solh
Calpain-15 (1031 aa)
     
        0.566
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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