Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PterPhosphotriesterase-related protein; Binds resiniferotoxin, a vanilloid that desensitizes nociceptive neurons. (349 aa)    
Predicted Functional Partners:
Tmem18
Transmembrane protein 18; Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats (By similarity). Cell migration modulator which enhances the glioma- specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC).
      
 0.571
Dennd4b
DENN domain-containing 4B.
    
 
 0.562
Reep5
Receptor expression-enhancing protein 5; May promote functional cell surface expression of olfactory receptors.
   
 
 0.519
Dram1
DNA-damage-regulated autophagy modulator 1.
      
 0.502
Rubcn
Rubicon autophagy regulator.
    
  0.502
Kctd15
Similar to potassium channel tetramerisation domain containing 15.
   
  
 0.501
Mybph
Myosin-binding protein H; Binds to myosin; probably involved in interaction with thick myofilaments in the A-band; Belongs to the immunoglobulin superfamily. MyBP family.
   
  
 0.500
Pop5
Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
   
  
 0.496
Coasy
Coenzyme A synthase.
   
 
 0.493
Dhx40
Probable ATP-dependent RNA helicase DHX40; Probable ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DEAH subfamily.
   
  
 0.493
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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