node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Alg1 | Dpm1 | ENSRNOP00000059348 | ENSRNOP00000016150 | Asparagine-linked glycosylation 1 homolog (Yeast, beta-1,4-mannosyltransferase) (Predicted). | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | 0.981 |
Alg1 | Dpm2 | ENSRNOP00000059348 | ENSRNOP00000065111 | Asparagine-linked glycosylation 1 homolog (Yeast, beta-1,4-mannosyltransferase) (Predicted). | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity. | 0.933 |
Alg1 | Dpm3 | ENSRNOP00000059348 | ENSRNOP00000049779 | Asparagine-linked glycosylation 1 homolog (Yeast, beta-1,4-mannosyltransferase) (Predicted). | Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. | 0.936 |
Alg1 | Gale | ENSRNOP00000059348 | ENSRNOP00000013322 | Asparagine-linked glycosylation 1 homolog (Yeast, beta-1,4-mannosyltransferase) (Predicted). | UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...] | 0.562 |
Alg1 | Gmds | ENSRNOP00000059348 | ENSRNOP00000023691 | Asparagine-linked glycosylation 1 homolog (Yeast, beta-1,4-mannosyltransferase) (Predicted). | GDP-mannose 4, 6-dehydratase. | 0.862 |
Alg1 | Gmppa | ENSRNOP00000059348 | ENSRNOP00000074442 | Asparagine-linked glycosylation 1 homolog (Yeast, beta-1,4-mannosyltransferase) (Predicted). | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. | 0.916 |
Alg1 | Gmppb | ENSRNOP00000059348 | ENSRNOP00000026854 | Asparagine-linked glycosylation 1 homolog (Yeast, beta-1,4-mannosyltransferase) (Predicted). | GDP-mannose pyrophosphorylase B (Predicted), isoform CRA_a. | 0.954 |
Dpm1 | Alg1 | ENSRNOP00000016150 | ENSRNOP00000059348 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | Asparagine-linked glycosylation 1 homolog (Yeast, beta-1,4-mannosyltransferase) (Predicted). | 0.981 |
Dpm1 | Dpm2 | ENSRNOP00000016150 | ENSRNOP00000065111 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity. | 0.995 |
Dpm1 | Dpm3 | ENSRNOP00000016150 | ENSRNOP00000049779 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. | 0.997 |
Dpm1 | Gale | ENSRNOP00000016150 | ENSRNOP00000013322 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...] | 0.491 |
Dpm1 | Gmds | ENSRNOP00000016150 | ENSRNOP00000023691 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | GDP-mannose 4, 6-dehydratase. | 0.866 |
Dpm1 | Gmppa | ENSRNOP00000016150 | ENSRNOP00000074442 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. | 0.942 |
Dpm1 | Gmppb | ENSRNOP00000016150 | ENSRNOP00000026854 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | GDP-mannose pyrophosphorylase B (Predicted), isoform CRA_a. | 0.968 |
Dpm1 | Mpi | ENSRNOP00000016150 | ENSRNOP00000025783 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | Mannose-6-phosphate isomerase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | 0.495 |
Dpm1 | Tsta3 | ENSRNOP00000016150 | ENSRNOP00000012306 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | Tissue specific transplantation antigen P35B (Predicted), isoform CRA_a. | 0.450 |
Dpm2 | Alg1 | ENSRNOP00000065111 | ENSRNOP00000059348 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity. | Asparagine-linked glycosylation 1 homolog (Yeast, beta-1,4-mannosyltransferase) (Predicted). | 0.933 |
Dpm2 | Dpm1 | ENSRNOP00000065111 | ENSRNOP00000016150 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity. | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | 0.995 |
Dpm2 | Dpm3 | ENSRNOP00000065111 | ENSRNOP00000049779 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity. | Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. | 0.999 |
Dpm2 | Gmds | ENSRNOP00000065111 | ENSRNOP00000023691 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity. | GDP-mannose 4, 6-dehydratase. | 0.805 |