node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ak9 | Dck | ENSRNOP00000054014 | ENSRNOP00000004440 | Adenylate kinase 9. | Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). | 0.924 |
Ak9 | Dctpp1 | ENSRNOP00000054014 | ENSRNOP00000024074 | Adenylate kinase 9. | dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. | 0.919 |
Ak9 | Nme1 | ENSRNOP00000054014 | ENSRNOP00000003658 | Adenylate kinase 9. | Nucleoside diphosphate kinase A; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for n [...] | 0.947 |
Ak9 | Nme2 | ENSRNOP00000054014 | ENSRNOP00000003611 | Adenylate kinase 9. | Nucleoside diphosphate kinase B; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically. Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III(1) region of the MYC gene promoter. Does not bind to duplex NHE I [...] | 0.947 |
Ak9 | Nme3 | ENSRNOP00000054014 | ENSRNOP00000021650 | Adenylate kinase 9. | Nucleoside diphosphate kinase. | 0.971 |
Ak9 | Nme6 | ENSRNOP00000054014 | ENSRNOP00000028125 | Adenylate kinase 9. | Nucleoside diphosphate kinase 6; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.971 |
Ak9 | Nt5m | ENSRNOP00000054014 | ENSRNOP00000004448 | Adenylate kinase 9. | 5',3'-nucleotidase, mitochondrial. | 0.705 |
Ak9 | Rrm1 | ENSRNOP00000054014 | ENSRNOP00000064166 | Adenylate kinase 9. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.995 |
Ak9 | Rrm2 | ENSRNOP00000054014 | ENSRNOP00000073334 | Adenylate kinase 9. | Ribonucleoside-diphosphate reductase subunit M2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). Inhibits Wnt signaling (By similarity); Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.985 |
Dck | Ak9 | ENSRNOP00000004440 | ENSRNOP00000054014 | Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). | Adenylate kinase 9. | 0.924 |
Dck | Dctd | ENSRNOP00000004440 | ENSRNOP00000017670 | Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). | Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase. | 0.979 |
Dck | Dctpp1 | ENSRNOP00000004440 | ENSRNOP00000024074 | Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). | dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. | 0.923 |
Dck | Nme3 | ENSRNOP00000004440 | ENSRNOP00000021650 | Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). | Nucleoside diphosphate kinase. | 0.434 |
Dck | Nme6 | ENSRNOP00000004440 | ENSRNOP00000028125 | Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). | Nucleoside diphosphate kinase 6; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.434 |
Dck | Nt5m | ENSRNOP00000004440 | ENSRNOP00000004448 | Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). | 5',3'-nucleotidase, mitochondrial. | 0.921 |
Dck | Rrm1 | ENSRNOP00000004440 | ENSRNOP00000064166 | Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.756 |
Dck | Rrm2 | ENSRNOP00000004440 | ENSRNOP00000073334 | Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). | Ribonucleoside-diphosphate reductase subunit M2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). Inhibits Wnt signaling (By similarity); Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.676 |
Dctd | Dck | ENSRNOP00000017670 | ENSRNOP00000004440 | Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase. | Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). | 0.979 |
Dctd | Dctpp1 | ENSRNOP00000017670 | ENSRNOP00000024074 | Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase. | dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. | 0.967 |
Dctd | Nt5m | ENSRNOP00000017670 | ENSRNOP00000004448 | Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase. | 5',3'-nucleotidase, mitochondrial. | 0.906 |