| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC103694883 | Slc5a1 | ENSRNOP00000073653 | ENSRNOP00000024165 | Sodium/glucose cotransporter 1-like; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.743 |
| LOC103694884 | Slc5a1 | ENSRNOP00000072375 | ENSRNOP00000024165 | Sodium/glucose cotransporter 1-like. | Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.771 |
| Lct | Si | ENSRNOP00000004908 | ENSRNOP00000045106 | Lactase-phlorizin hydrolase; LPH splits lactose in the small intestine; Belongs to the glycosyl hydrolase 1 family. | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family. | 0.858 |
| Lct | Slc2a2 | ENSRNOP00000004908 | ENSRNOP00000015866 | Lactase-phlorizin hydrolase; LPH splits lactose in the small intestine; Belongs to the glycosyl hydrolase 1 family. | Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney (By similarity). Also able to mediate the transport of dehydroascorbate (By simil [...] | 0.416 |
| Lct | Slc2a5 | ENSRNOP00000004908 | ENSRNOP00000068562 | Lactase-phlorizin hydrolase; LPH splits lactose in the small intestine; Belongs to the glycosyl hydrolase 1 family. | Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine (By similarity). Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose (By similarity). Required for the development of high blood pressure in response to high dietary fructose intake (By similarity). | 0.408 |
| Lct | Slc5a1 | ENSRNOP00000004908 | ENSRNOP00000024165 | Lactase-phlorizin hydrolase; LPH splits lactose in the small intestine; Belongs to the glycosyl hydrolase 1 family. | Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.716 |
| RGD1563815 | Slc5a1 | ENSRNOP00000069755 | ENSRNOP00000024165 | Sodium/glucose cotransporter 1-like; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.771 |
| Si | Lct | ENSRNOP00000045106 | ENSRNOP00000004908 | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family. | Lactase-phlorizin hydrolase; LPH splits lactose in the small intestine; Belongs to the glycosyl hydrolase 1 family. | 0.858 |
| Si | Slc15a1 | ENSRNOP00000045106 | ENSRNOP00000015890 | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family. | Solute carrier family 15 member 1; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. | 0.631 |
| Si | Slc2a2 | ENSRNOP00000045106 | ENSRNOP00000015866 | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family. | Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney (By similarity). Also able to mediate the transport of dehydroascorbate (By simil [...] | 0.585 |
| Si | Slc2a5 | ENSRNOP00000045106 | ENSRNOP00000068562 | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family. | Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine (By similarity). Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose (By similarity). Required for the development of high blood pressure in response to high dietary fructose intake (By similarity). | 0.573 |
| Si | Slc5a1 | ENSRNOP00000045106 | ENSRNOP00000024165 | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family. | Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.714 |
| Si | Tas1r3 | ENSRNOP00000045106 | ENSRNOP00000026671 | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family. | Taste receptor type 1 member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, but not to their D-enantiomers or other compounds. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses (By similarity). | 0.540 |
| Slc15a1 | Si | ENSRNOP00000015890 | ENSRNOP00000045106 | Solute carrier family 15 member 1; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family. | 0.631 |
| Slc15a1 | Slc2a2 | ENSRNOP00000015890 | ENSRNOP00000015866 | Solute carrier family 15 member 1; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. | Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney (By similarity). Also able to mediate the transport of dehydroascorbate (By simil [...] | 0.776 |
| Slc15a1 | Slc2a5 | ENSRNOP00000015890 | ENSRNOP00000068562 | Solute carrier family 15 member 1; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. | Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine (By similarity). Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose (By similarity). Required for the development of high blood pressure in response to high dietary fructose intake (By similarity). | 0.683 |
| Slc15a1 | Slc5a1 | ENSRNOP00000015890 | ENSRNOP00000024165 | Solute carrier family 15 member 1; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. | Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.768 |
| Slc15a1 | Slc9a3 | ENSRNOP00000015890 | ENSRNOP00000020711 | Solute carrier family 15 member 1; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. | Sodium/hydrogen exchanger 3; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.623 |
| Slc15a1 | Tas1r3 | ENSRNOP00000015890 | ENSRNOP00000026671 | Solute carrier family 15 member 1; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. | Taste receptor type 1 member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, but not to their D-enantiomers or other compounds. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses (By similarity). | 0.503 |
| Slc2a2 | Lct | ENSRNOP00000015866 | ENSRNOP00000004908 | Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney (By similarity). Also able to mediate the transport of dehydroascorbate (By simil [...] | Lactase-phlorizin hydrolase; LPH splits lactose in the small intestine; Belongs to the glycosyl hydrolase 1 family. | 0.416 |
