node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ctsg | F2rl2 | ENSRNOP00000056429 | ENSRNOP00000024292 | Cathepsin G. | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | 0.679 |
Ctsg | F2rl3 | ENSRNOP00000056429 | ENSRNOP00000065190 | Cathepsin G. | Proteinase-activated receptor 4; Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. | 0.728 |
Ctsg | Mcpt10 | ENSRNOP00000056429 | ENSRNOP00000066083 | Cathepsin G. | Granzyme-like protein 2; This enzyme is necessary for target cell lysis in cell- mediated immune responses; Belongs to the peptidase S1 family. Granzyme subfamily. | 0.909 |
F2 | F2rl2 | ENSRNOP00000022233 | ENSRNOP00000024292 | Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | 0.915 |
F2 | F2rl3 | ENSRNOP00000022233 | ENSRNOP00000065190 | Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Proteinase-activated receptor 4; Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. | 0.998 |
F2 | Plg | ENSRNOP00000022233 | ENSRNOP00000023370 | Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasmin heavy chain A, short form; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invas [...] | 0.955 |
F2rl2 | Ctsg | ENSRNOP00000024292 | ENSRNOP00000056429 | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | Cathepsin G. | 0.679 |
F2rl2 | F2 | ENSRNOP00000024292 | ENSRNOP00000022233 | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.915 |
F2rl2 | F2rl3 | ENSRNOP00000024292 | ENSRNOP00000065190 | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | Proteinase-activated receptor 4; Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. | 0.919 |
F2rl2 | Gzma | ENSRNOP00000024292 | ENSRNOP00000014134 | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | Granzyme A; Belongs to the peptidase S1 family. | 0.669 |
F2rl2 | LOC286960 | ENSRNOP00000024292 | ENSRNOP00000017852 | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | Trypsin-4; Belongs to the peptidase S1 family. | 0.664 |
F2rl2 | LOC312273 | ENSRNOP00000024292 | ENSRNOP00000017673 | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | Trypsin V-A. | 0.659 |
F2rl2 | Mcpt10 | ENSRNOP00000024292 | ENSRNOP00000066083 | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | Granzyme-like protein 2; This enzyme is necessary for target cell lysis in cell- mediated immune responses; Belongs to the peptidase S1 family. Granzyme subfamily. | 0.680 |
F2rl2 | Plg | ENSRNOP00000024292 | ENSRNOP00000023370 | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | Plasmin heavy chain A, short form; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invas [...] | 0.658 |
F2rl2 | Prss2 | ENSRNOP00000024292 | ENSRNOP00000018853 | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | Anionic trypsin-2; Belongs to the peptidase S1 family. | 0.658 |
F2rl2 | Prss3 | ENSRNOP00000024292 | ENSRNOP00000018042 | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | Cationic trypsin-3. | 0.658 |
F2rl3 | Ctsg | ENSRNOP00000065190 | ENSRNOP00000056429 | Proteinase-activated receptor 4; Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. | Cathepsin G. | 0.728 |
F2rl3 | F2 | ENSRNOP00000065190 | ENSRNOP00000022233 | Proteinase-activated receptor 4; Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. | Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.998 |
F2rl3 | F2rl2 | ENSRNOP00000065190 | ENSRNOP00000024292 | Proteinase-activated receptor 4; Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. | Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; Belongs to the G-protein coupled receptor 1 family. | 0.919 |
F2rl3 | Gzma | ENSRNOP00000065190 | ENSRNOP00000014134 | Proteinase-activated receptor 4; Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. | Granzyme A; Belongs to the peptidase S1 family. | 0.689 |