node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cd2 | Cd37 | ENSRNOP00000021268 | ENSRNOP00000059092 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | Leukocyte antigen CD37. | 0.489 |
Cd2 | Cd48 | ENSRNOP00000021268 | ENSRNOP00000006306 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | 0.958 |
Cd2 | Cd53 | ENSRNOP00000021268 | ENSRNOP00000024344 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); Belongs to the tetraspanin (TM4SF) family. | 0.708 |
Cd2 | Itgb2 | ENSRNOP00000021268 | ENSRNOP00000001639 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | Integrin beta. | 0.557 |
Cd2 | Lcp2 | ENSRNOP00000021268 | ENSRNOP00000050879 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | Lymphocyte cytosolic protein 2. | 0.518 |
Cd2 | Ptprc | ENSRNOP00000021268 | ENSRNOP00000063859 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | Receptor-type tyrosine-protein phosphatase C; Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). | 0.690 |
Cd37 | Cd2 | ENSRNOP00000059092 | ENSRNOP00000021268 | Leukocyte antigen CD37. | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | 0.489 |
Cd37 | Cd48 | ENSRNOP00000059092 | ENSRNOP00000006306 | Leukocyte antigen CD37. | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | 0.401 |
Cd37 | Cd53 | ENSRNOP00000059092 | ENSRNOP00000024344 | Leukocyte antigen CD37. | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); Belongs to the tetraspanin (TM4SF) family. | 0.692 |
Cd37 | Cd82 | ENSRNOP00000059092 | ENSRNOP00000000052 | Leukocyte antigen CD37. | CD82 antigen; Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway. | 0.742 |
Cd37 | Laptm5 | ENSRNOP00000059092 | ENSRNOP00000015198 | Leukocyte antigen CD37. | Lysosomal-associated protein transmembrane 5. | 0.469 |
Cd37 | Ptprc | ENSRNOP00000059092 | ENSRNOP00000063859 | Leukocyte antigen CD37. | Receptor-type tyrosine-protein phosphatase C; Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). | 0.451 |
Cd48 | Cd2 | ENSRNOP00000006306 | ENSRNOP00000021268 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | 0.958 |
Cd48 | Cd37 | ENSRNOP00000006306 | ENSRNOP00000059092 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | Leukocyte antigen CD37. | 0.401 |
Cd48 | Cd53 | ENSRNOP00000006306 | ENSRNOP00000024344 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); Belongs to the tetraspanin (TM4SF) family. | 0.789 |
Cd48 | Ctss | ENSRNOP00000006306 | ENSRNOP00000028732 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | Cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L (By similarity). May be involved in thyroid hormone biosynthesis. Belongs to the peptidase C1 family. | 0.425 |
Cd48 | Itgb2 | ENSRNOP00000006306 | ENSRNOP00000001639 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | Integrin beta. | 0.571 |
Cd48 | Laptm5 | ENSRNOP00000006306 | ENSRNOP00000015198 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | Lysosomal-associated protein transmembrane 5. | 0.653 |
Cd48 | Lcp2 | ENSRNOP00000006306 | ENSRNOP00000050879 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | Lymphocyte cytosolic protein 2. | 0.464 |
Cd48 | Ptprc | ENSRNOP00000006306 | ENSRNOP00000063859 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | Receptor-type tyrosine-protein phosphatase C; Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). | 0.833 |