STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rbm5RNA-binding protein 5; Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate apoptosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes production of a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes production of a catalytically active form of CASP2/Cas [...] (815 aa)    
Predicted Functional Partners:
Rbm25l1
RNA-binding motif protein 25-like 1.
   
  
 0.885
Rbm39
RNA-binding region (RNP1, RRM) containing 2, isoform CRA_f.
   
 
 0.792
Dhx15
DEAH (Asp-Glu-Ala-His) box polypeptide 15 (Predicted), isoform CRA_b.
   
 
 0.772
LOC100910882
RNA-binding protein 39-like.
   
 
 0.758
Luc7l3
Similar to cisplatin resistance-associated overexpressed protein (Predicted).
   
 
 0.756
U2af2
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
   
 
 0.753
Nol6
Nucleolar protein 6.
   
 
 0.670
Sugp1
SURP and G-patch domain-containing protein 1; Plays a role in pre-mRNA splicing.
   
 
0.665
Srsf11
Similar to splicing factor p54, isoform CRA_c.
   
 
 0.597
Gpkow
G patch domain and KOW motifs.
   
 
 0.588
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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