node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acr | Acrbp | ENSRNOP00000046900 | ENSRNOP00000024618 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | 0.685 |
Acr | Izumo1 | ENSRNOP00000046900 | ENSRNOP00000035119 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Izumo sperm-egg fusion protein 1; Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. | 0.786 |
Acr | Spaca1 | ENSRNOP00000046900 | ENSRNOP00000010909 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Similar to RIKEN cDNA 4930540L03 (Predicted). | 0.407 |
Acr | Zp3r | ENSRNOP00000046900 | ENSRNOP00000031964 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Zona pellucida sperm-binding protein 3 receptor; Binds to ZP3 glycoprotein in egg zona pellucida. Probably involved in interactions between sperm acrosome and egg zona pellucida during and immediately following the acrosome reaction (By similarity). | 0.558 |
Acr | Zpbp | ENSRNOP00000046900 | ENSRNOP00000030318 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Zona pellucida binding protein, isoform CRA_b. | 0.432 |
Acr | Zpbp2 | ENSRNOP00000046900 | ENSRNOP00000048783 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Zona pellucida-binding protein 2; Is implicated in sperm-oocyte interaction during fertilization; Belongs to the zona pellucida-binding protein Sp38 family. | 0.494 |
Acrbp | Acr | ENSRNOP00000024618 | ENSRNOP00000046900 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | 0.685 |
Acrbp | Dpy19l2 | ENSRNOP00000024618 | ENSRNOP00000067167 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Dpy-19-like 2. | 0.665 |
Acrbp | Izumo1 | ENSRNOP00000024618 | ENSRNOP00000035119 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Izumo sperm-egg fusion protein 1; Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. | 0.604 |
Acrbp | Odf1 | ENSRNOP00000024618 | ENSRNOP00000008700 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | 0.592 |
Acrbp | Pcsk4 | ENSRNOP00000024618 | ENSRNOP00000022358 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Proprotein convertase subtilisin/kexin type 4; Proprotein convertase involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. In males, important for ADAM2 processing as well as other acrosomal proteins with roles in fertilization and critical for normal fertilization events such as sperm capacitation, acrosome reaction and binding of sperm to zona pellucida (By similarity). Plays also a role in female fertility, involved in the regulation of trophoblast migration and placental development, may be through the proteolyt [...] | 0.580 |
Acrbp | Pkdrej | ENSRNOP00000024618 | ENSRNOP00000048039 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Polycystin family receptor for egg jelly. | 0.600 |
Acrbp | Spaca1 | ENSRNOP00000024618 | ENSRNOP00000010909 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Similar to RIKEN cDNA 4930540L03 (Predicted). | 0.624 |
Acrbp | Zp3r | ENSRNOP00000024618 | ENSRNOP00000031964 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Zona pellucida sperm-binding protein 3 receptor; Binds to ZP3 glycoprotein in egg zona pellucida. Probably involved in interactions between sperm acrosome and egg zona pellucida during and immediately following the acrosome reaction (By similarity). | 0.624 |
Acrbp | Zpbp | ENSRNOP00000024618 | ENSRNOP00000030318 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Zona pellucida binding protein, isoform CRA_b. | 0.639 |
Acrbp | Zpbp2 | ENSRNOP00000024618 | ENSRNOP00000048783 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Zona pellucida-binding protein 2; Is implicated in sperm-oocyte interaction during fertilization; Belongs to the zona pellucida-binding protein Sp38 family. | 0.794 |
Dpy19l2 | Acrbp | ENSRNOP00000067167 | ENSRNOP00000024618 | Dpy-19-like 2. | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | 0.665 |
Dpy19l2 | Izumo1 | ENSRNOP00000067167 | ENSRNOP00000035119 | Dpy-19-like 2. | Izumo sperm-egg fusion protein 1; Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. | 0.574 |
Dpy19l2 | Odf1 | ENSRNOP00000067167 | ENSRNOP00000008700 | Dpy-19-like 2. | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | 0.469 |
Dpy19l2 | Pcsk4 | ENSRNOP00000067167 | ENSRNOP00000022358 | Dpy-19-like 2. | Proprotein convertase subtilisin/kexin type 4; Proprotein convertase involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. In males, important for ADAM2 processing as well as other acrosomal proteins with roles in fertilization and critical for normal fertilization events such as sperm capacitation, acrosome reaction and binding of sperm to zona pellucida (By similarity). Plays also a role in female fertility, involved in the regulation of trophoblast migration and placental development, may be through the proteolyt [...] | 0.558 |