Anapc10 protein (Rattus norvegicus) - STRING interaction network

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Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Anapc10	Anapc13	ENSRNOP00000024689	ENSRNOP00000011203	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	Anaphase-promoting complex subunit 13.	0.999
Anapc10	Anapc15	ENSRNOP00000024689	ENSRNOP00000027028	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	Anaphase-promoting complex subunit 15; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby contributing to the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20 (By similarity).	0.999
Anapc10	Anapc16	ENSRNOP00000024689	ENSRNOP00000000702	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	Anaphase-promoting complex subunit 16.	0.999
Anapc10	Anapc2	ENSRNOP00000024689	ENSRNOP00000015099	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	Anaphase-promoting complex subunit 2; Belongs to the cullin family.	0.999
Anapc10	Anapc5	ENSRNOP00000024689	ENSRNOP00000001794	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).	0.999
Anapc10	Anapc7	ENSRNOP00000024689	ENSRNOP00000001729	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	Anaphase promoting complex subunit 7 (Predicted).	0.999
Anapc10	Cdc16	ENSRNOP00000024689	ENSRNOP00000023736	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	CDC16 cell division cycle 16 homolog (S. cerevisiae).	0.999
Anapc10	Cdc20	ENSRNOP00000024689	ENSRNOP00000037772	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...]	0.999
Anapc10	Cdc23	ENSRNOP00000024689	ENSRNOP00000035675	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	CDC23 (Cell division cycle 23, yeast, homolog), isoform CRA_b.	0.999
Anapc10	Cdc27	ENSRNOP00000024689	ENSRNOP00000007963	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	Cell division cycle protein 27 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).	0.999
Anapc13	Anapc10	ENSRNOP00000011203	ENSRNOP00000024689	Anaphase-promoting complex subunit 13.	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	0.999
Anapc13	Anapc15	ENSRNOP00000011203	ENSRNOP00000027028	Anaphase-promoting complex subunit 13.	Anaphase-promoting complex subunit 15; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby contributing to the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20 (By similarity).	0.997
Anapc13	Anapc16	ENSRNOP00000011203	ENSRNOP00000000702	Anaphase-promoting complex subunit 13.	Anaphase-promoting complex subunit 16.	0.999
Anapc13	Anapc2	ENSRNOP00000011203	ENSRNOP00000015099	Anaphase-promoting complex subunit 13.	Anaphase-promoting complex subunit 2; Belongs to the cullin family.	0.998
Anapc13	Anapc5	ENSRNOP00000011203	ENSRNOP00000001794	Anaphase-promoting complex subunit 13.	Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).	0.999
Anapc13	Anapc7	ENSRNOP00000011203	ENSRNOP00000001729	Anaphase-promoting complex subunit 13.	Anaphase promoting complex subunit 7 (Predicted).	0.998
Anapc13	Cdc16	ENSRNOP00000011203	ENSRNOP00000023736	Anaphase-promoting complex subunit 13.	CDC16 cell division cycle 16 homolog (S. cerevisiae).	0.998
Anapc13	Cdc20	ENSRNOP00000011203	ENSRNOP00000037772	Anaphase-promoting complex subunit 13.	Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...]	0.998
Anapc13	Cdc23	ENSRNOP00000011203	ENSRNOP00000035675	Anaphase-promoting complex subunit 13.	CDC23 (Cell division cycle 23, yeast, homolog), isoform CRA_b.	0.999
Anapc13	Cdc27	ENSRNOP00000011203	ENSRNOP00000007963	Anaphase-promoting complex subunit 13.	Cell division cycle protein 27 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).	0.998

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