STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Thap4THAP domain-containing protein 4. (569 aa)    
Predicted Functional Partners:
Thap3
THAP domain containing, apoptosis associated protein 3 (Predicted).
   
  
0.672
Mrps2
Mitochondrial ribosomal protein S2.
   
    0.597
Thap7
THAP domain containing 7, isoform CRA_b.
   
  
0.556
Thap12
THAP domain-containing 12.
   
  
 0.549
Ankmy1
Ankyrin repeat and MYND domain-containing 1.
      
 0.467
Stk25
Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a.
   
  
 0.431
U2af2
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
      
 0.422
Strbp
Spermatid perinuclear RNA-binding protein; Involved in spermatogenesis and sperm function (By similarity). Plays a role in regulation of cell growth. Binds to double-stranded DNA and RNA. Binds most efficiently to poly(I:C) RNA than to poly(dI:dC) DNA. Binds also to single-stranded poly(G) RNA. Binds non-specifically to the mRNA PRM1 3'-UTR and adenovirus VA RNA (By similarity).
   
  
 0.419
Hcfc1
Host cell factor C1.
   
  
 0.412
Ctbp1
C-terminal-binding protein 1; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
   
  
 0.410
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.