Cd74 protein (Rattus norvegicus) - STRING interaction network

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Cd74

H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. (280 aa)

Predicted Functional Partners:

RT1-Db1

0.999

RT1-Ba

0.999

RT1-Bb

0.999

RT1-Da

0.999

RT1-Ha

0.998

RT1-DOb

0.995

RT1-DOa

0.995

RT1-DMa

0.995

RT1-DMb

0.992

RT1-Db2

0.986

Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd74	RT1-Ba	ENSRNOP00000025354	ENSRNOP00000000523	H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.	Rano class II histocompatibility antigen, B alpha chain.	0.999
Cd74	RT1-Bb	ENSRNOP00000025354	ENSRNOP00000000525	H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.	Rano class II histocompatibility antigen, B-1 beta chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class II family.	0.999
Cd74	RT1-DMa	ENSRNOP00000025354	ENSRNOP00000066343	H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.	0.995
Cd74	RT1-DMb	ENSRNOP00000025354	ENSRNOP00000065741	H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.	Major histocompatibility complex, class II, DM beta, isoform CRA_a.	0.992
Cd74	RT1-DOa	ENSRNOP00000025354	ENSRNOP00000034452	H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.	RT1 class II, locus DOa; Belongs to the MHC class II family.	0.995
Cd74	RT1-DOb	ENSRNOP00000025354	ENSRNOP00000000526	H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.	RT1 class II, locus DOb.	0.995
Cd74	RT1-Da	ENSRNOP00000025354	ENSRNOP00000048774	H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.	Histocompatibility 2, class II antigen E alpha; Belongs to the MHC class II family.	0.999
Cd74	RT1-Db1	ENSRNOP00000025354	ENSRNOP00000000522	H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.	Rano class II histocompatibility antigen, D-1 beta chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class II family.	0.999
Cd74	RT1-Db2	ENSRNOP00000025354	ENSRNOP00000042899	H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.	MHC class II beta chain.	0.986
Cd74	RT1-Ha	ENSRNOP00000025354	ENSRNOP00000033818	H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.	RT1 class II, locus Ha; Belongs to the MHC class II family.	0.998
RT1-Ba	Cd74	ENSRNOP00000000523	ENSRNOP00000025354	Rano class II histocompatibility antigen, B alpha chain.	H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.	0.999
RT1-Ba	RT1-Bb	ENSRNOP00000000523	ENSRNOP00000000525	Rano class II histocompatibility antigen, B alpha chain.	Rano class II histocompatibility antigen, B-1 beta chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class II family.	0.999
RT1-Ba	RT1-DMa	ENSRNOP00000000523	ENSRNOP00000066343	Rano class II histocompatibility antigen, B alpha chain.	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.	0.989
RT1-Ba	RT1-DMb	ENSRNOP00000000523	ENSRNOP00000065741	Rano class II histocompatibility antigen, B alpha chain.	Major histocompatibility complex, class II, DM beta, isoform CRA_a.	0.989
RT1-Ba	RT1-DOa	ENSRNOP00000000523	ENSRNOP00000034452	Rano class II histocompatibility antigen, B alpha chain.	RT1 class II, locus DOa; Belongs to the MHC class II family.	0.991
RT1-Ba	RT1-DOb	ENSRNOP00000000523	ENSRNOP00000000526	Rano class II histocompatibility antigen, B alpha chain.	RT1 class II, locus DOb.	0.997
RT1-Ba	RT1-Da	ENSRNOP00000000523	ENSRNOP00000048774	Rano class II histocompatibility antigen, B alpha chain.	Histocompatibility 2, class II antigen E alpha; Belongs to the MHC class II family.	0.995
RT1-Ba	RT1-Db1	ENSRNOP00000000523	ENSRNOP00000000522	Rano class II histocompatibility antigen, B alpha chain.	Rano class II histocompatibility antigen, D-1 beta chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class II family.	0.999
RT1-Ba	RT1-Db2	ENSRNOP00000000523	ENSRNOP00000042899	Rano class II histocompatibility antigen, B alpha chain.	MHC class II beta chain.	0.933
RT1-Ba	RT1-Ha	ENSRNOP00000000523	ENSRNOP00000033818	Rano class II histocompatibility antigen, B alpha chain.	RT1 class II, locus Ha; Belongs to the MHC class II family.	0.992

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