node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dppa4 | Thap11 | ENSRNOP00000062176 | ENSRNOP00000025815 | Developmental pluripotency-associated protein 4; May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic stem (ES) cells into a primitive ectoderm lineage (By similarity). | THAP domain containing 11 (Predicted). | 0.499 |
Dtl | Mcm2 | ENSRNOP00000005576 | ENSRNOP00000022231 | Denticleless E3 ubiquitin protein ligase homolog. | DNA helicase; Belongs to the MCM family. | 0.797 |
Dtl | Mcm3 | ENSRNOP00000005576 | ENSRNOP00000017081 | Denticleless E3 ubiquitin protein ligase homolog. | DNA helicase; Belongs to the MCM family. | 0.657 |
Dtl | Mcm9 | ENSRNOP00000005576 | ENSRNOP00000004499 | Denticleless E3 ubiquitin protein ligase homolog. | DNA helicase MCM9; Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross- links (ICLs) by homologous recombination (HR). Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex nuclease activity. Probably by regulating the localization of the MRN complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs. Acts as a helicase in DNA mismatch repair (MMR) followin [...] | 0.502 |
Dtl | Orc1 | ENSRNOP00000005576 | ENSRNOP00000012492 | Denticleless E3 ubiquitin protein ligase homolog. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity). | 0.859 |
Dtl | Prim2 | ENSRNOP00000005576 | ENSRNOP00000016828 | Denticleless E3 ubiquitin protein ligase homolog. | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis (By similarity). During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1, an accessory subunit POLA2 and two primase subunits, the catalytic subunit PRIM1 and the regulatory subunit PRIM2) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1 (By similarity) [...] | 0.795 |
Dtl | Rfc4 | ENSRNOP00000005576 | ENSRNOP00000002487 | Denticleless E3 ubiquitin protein ligase homolog. | Replication factor C (Activator 1) 4 (Predicted), isoform CRA_a. | 0.689 |
Dtl | Thap11 | ENSRNOP00000005576 | ENSRNOP00000025815 | Denticleless E3 ubiquitin protein ligase homolog. | THAP domain containing 11 (Predicted). | 0.422 |
Gart | Thap11 | ENSRNOP00000033253 | ENSRNOP00000025815 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | THAP domain containing 11 (Predicted). | 0.672 |
Mcm2 | Dtl | ENSRNOP00000022231 | ENSRNOP00000005576 | DNA helicase; Belongs to the MCM family. | Denticleless E3 ubiquitin protein ligase homolog. | 0.797 |
Mcm2 | Mcm3 | ENSRNOP00000022231 | ENSRNOP00000017081 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
Mcm2 | Mcm9 | ENSRNOP00000022231 | ENSRNOP00000004499 | DNA helicase; Belongs to the MCM family. | DNA helicase MCM9; Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross- links (ICLs) by homologous recombination (HR). Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex nuclease activity. Probably by regulating the localization of the MRN complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs. Acts as a helicase in DNA mismatch repair (MMR) followin [...] | 0.720 |
Mcm2 | Orc1 | ENSRNOP00000022231 | ENSRNOP00000012492 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity). | 0.996 |
Mcm2 | Prim2 | ENSRNOP00000022231 | ENSRNOP00000016828 | DNA helicase; Belongs to the MCM family. | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis (By similarity). During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1, an accessory subunit POLA2 and two primase subunits, the catalytic subunit PRIM1 and the regulatory subunit PRIM2) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1 (By similarity) [...] | 0.946 |
Mcm2 | Rfc4 | ENSRNOP00000022231 | ENSRNOP00000002487 | DNA helicase; Belongs to the MCM family. | Replication factor C (Activator 1) 4 (Predicted), isoform CRA_a. | 0.896 |
Mcm2 | Thap11 | ENSRNOP00000022231 | ENSRNOP00000025815 | DNA helicase; Belongs to the MCM family. | THAP domain containing 11 (Predicted). | 0.467 |
Mcm3 | Dtl | ENSRNOP00000017081 | ENSRNOP00000005576 | DNA helicase; Belongs to the MCM family. | Denticleless E3 ubiquitin protein ligase homolog. | 0.657 |
Mcm3 | Mcm2 | ENSRNOP00000017081 | ENSRNOP00000022231 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
Mcm3 | Mcm9 | ENSRNOP00000017081 | ENSRNOP00000004499 | DNA helicase; Belongs to the MCM family. | DNA helicase MCM9; Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross- links (ICLs) by homologous recombination (HR). Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex nuclease activity. Probably by regulating the localization of the MRN complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs. Acts as a helicase in DNA mismatch repair (MMR) followin [...] | 0.992 |
Mcm3 | Orc1 | ENSRNOP00000017081 | ENSRNOP00000012492 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity). | 0.995 |