node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Actn2 | Casq1 | ENSRNOP00000024098 | ENSRNOP00000009344 | Actinin alpha 2. | Calsequestrin-1; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction (By similarity). Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity). | 0.504 |
Actn2 | Myh15 | ENSRNOP00000024098 | ENSRNOP00000070522 | Actinin alpha 2. | Myosin, heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.443 |
Actn2 | Myh3 | ENSRNOP00000024098 | ENSRNOP00000004147 | Actinin alpha 2. | Myosin-3; Muscle contraction. | 0.837 |
Actn2 | Myh8 | ENSRNOP00000024098 | ENSRNOP00000054082 | Actinin alpha 2. | Myosin-8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.508 |
Actn2 | Myom2 | ENSRNOP00000024098 | ENSRNOP00000015908 | Actinin alpha 2. | Myomesin 2. | 0.670 |
Actn2 | Myoz3 | ENSRNOP00000024098 | ENSRNOP00000025989 | Actinin alpha 2. | Myozenin 3. | 0.518 |
Actn2 | Tnnc2 | ENSRNOP00000024098 | ENSRNOP00000020348 | Actinin alpha 2. | Troponin C2, fast skeletal type. | 0.824 |
Actn2 | Tnni2 | ENSRNOP00000024098 | ENSRNOP00000068190 | Actinin alpha 2. | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.814 |
Asb12 | Casq1 | ENSRNOP00000005663 | ENSRNOP00000009344 | Ankyrin repeat and SOCS box-containing 12. | Calsequestrin-1; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction (By similarity). Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity). | 0.546 |
Asb12 | Myoz3 | ENSRNOP00000005663 | ENSRNOP00000025989 | Ankyrin repeat and SOCS box-containing 12. | Myozenin 3. | 0.561 |
Casq1 | Actn2 | ENSRNOP00000009344 | ENSRNOP00000024098 | Calsequestrin-1; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction (By similarity). Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity). | Actinin alpha 2. | 0.504 |
Casq1 | Asb12 | ENSRNOP00000009344 | ENSRNOP00000005663 | Calsequestrin-1; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction (By similarity). Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity). | Ankyrin repeat and SOCS box-containing 12. | 0.546 |
Casq1 | Myh8 | ENSRNOP00000009344 | ENSRNOP00000054082 | Calsequestrin-1; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction (By similarity). Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity). | Myosin-8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.408 |
Casq1 | Myom2 | ENSRNOP00000009344 | ENSRNOP00000015908 | Calsequestrin-1; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction (By similarity). Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity). | Myomesin 2. | 0.678 |
Casq1 | Myoz3 | ENSRNOP00000009344 | ENSRNOP00000025989 | Calsequestrin-1; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction (By similarity). Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity). | Myozenin 3. | 0.547 |
Casq1 | Tnnc2 | ENSRNOP00000009344 | ENSRNOP00000020348 | Calsequestrin-1; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction (By similarity). Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity). | Troponin C2, fast skeletal type. | 0.594 |
Casq1 | Tnni2 | ENSRNOP00000009344 | ENSRNOP00000068190 | Calsequestrin-1; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction (By similarity). Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity). | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.716 |
Entpd5 | Myom2 | ENSRNOP00000041026 | ENSRNOP00000015908 | Ectonucleoside triphosphate diphosphohydrolase 5; Uridine diphosphatase (UDPase) that promotes protein N- glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thia [...] | Myomesin 2. | 0.506 |
Entpd5 | Myoz3 | ENSRNOP00000041026 | ENSRNOP00000025989 | Ectonucleoside triphosphate diphosphohydrolase 5; Uridine diphosphatase (UDPase) that promotes protein N- glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thia [...] | Myozenin 3. | 0.525 |
Myh15 | Actn2 | ENSRNOP00000070522 | ENSRNOP00000024098 | Myosin, heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Actinin alpha 2. | 0.443 |