node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ephx1 | Gsta1 | ENSRNOP00000004780 | ENSRNOP00000018325 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | 0.868 |
Ephx1 | Gsta4 | ENSRNOP00000004780 | ENSRNOP00000075572 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. | Glutathione S-transferase alpha-4; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. | 0.811 |
Ephx1 | Gstk1 | ENSRNOP00000004780 | ENSRNOP00000022275 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | 0.758 |
Ephx1 | Gstm4 | ENSRNOP00000004780 | ENSRNOP00000025994 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. | Glutathione S-transferase. | 0.789 |
Ephx1 | Gsto1 | ENSRNOP00000004780 | ENSRNOP00000016851 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | 0.797 |
Ephx1 | Gsto2 | ENSRNOP00000004780 | ENSRNOP00000017186 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. | Glutathione S-transferase omega-2; Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA). Belongs to the GST superfamily. Omega family. | 0.734 |
Ephx1 | Gstt1 | ENSRNOP00000004780 | ENSRNOP00000001669 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. | Glutathione S-transferase theta-1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity. | 0.831 |
Ephx1 | Gstt2 | ENSRNOP00000004780 | ENSRNOP00000071112 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. | Glutathione S-transferase theta-2; Catalyzes the inactivation of reactive sulfate esters in carcinogenic arylmethanols. Highest activity towards ethacrynic acid and cumene hydroperoxide. | 0.770 |
Ephx1 | Gstt3 | ENSRNOP00000004780 | ENSRNOP00000055038 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. | Similar to Glutathione S-transferase, theta 3 (Predicted); Belongs to the GST superfamily. | 0.734 |
Gss | Gsta1 | ENSRNOP00000025657 | ENSRNOP00000018325 | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family. | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | 0.789 |
Gss | Gsta4 | ENSRNOP00000025657 | ENSRNOP00000075572 | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family. | Glutathione S-transferase alpha-4; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. | 0.803 |
Gss | Gstk1 | ENSRNOP00000025657 | ENSRNOP00000022275 | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family. | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | 0.744 |
Gss | Gstm4 | ENSRNOP00000025657 | ENSRNOP00000025994 | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family. | Glutathione S-transferase. | 0.779 |
Gss | Gsto1 | ENSRNOP00000025657 | ENSRNOP00000016851 | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family. | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | 0.860 |
Gss | Gsto2 | ENSRNOP00000025657 | ENSRNOP00000017186 | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family. | Glutathione S-transferase omega-2; Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA). Belongs to the GST superfamily. Omega family. | 0.768 |
Gss | Gstt1 | ENSRNOP00000025657 | ENSRNOP00000001669 | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family. | Glutathione S-transferase theta-1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity. | 0.792 |
Gss | Gstt2 | ENSRNOP00000025657 | ENSRNOP00000071112 | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family. | Glutathione S-transferase theta-2; Catalyzes the inactivation of reactive sulfate esters in carcinogenic arylmethanols. Highest activity towards ethacrynic acid and cumene hydroperoxide. | 0.809 |
Gss | Gstt3 | ENSRNOP00000025657 | ENSRNOP00000055038 | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family. | Similar to Glutathione S-transferase, theta 3 (Predicted); Belongs to the GST superfamily. | 0.715 |
Gsta1 | Ephx1 | ENSRNOP00000018325 | ENSRNOP00000004780 | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. | 0.868 |
Gsta1 | Gss | ENSRNOP00000018325 | ENSRNOP00000025657 | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family. | 0.789 |