node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Alpi | Gch1 | ENSRNOP00000026190 | ENSRNOP00000014821 | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | GTP cyclohydrolase 1; May positively regulate nitric oxide synthesis in endothelial cells. May be involved in dopamine synthesis (By similarity). May modify pain sensitivity and persistence; Belongs to the GTP cyclohydrolase I family. | 0.903 |
Alpi | Ggt5 | ENSRNOP00000026190 | ENSRNOP00000076289 | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | 0.675 |
Alpi | Ggt6 | ENSRNOP00000026190 | ENSRNOP00000039691 | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates. | 0.737 |
Alpi | Ggt7 | ENSRNOP00000026190 | ENSRNOP00000025315 | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | Glutathione hydrolase 7 heavy chain; Cleaves glutathione conjugates. | 0.723 |
Alpi | Got1 | ENSRNOP00000026190 | ENSRNOP00000022309 | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.720 |
Alpi | Got2 | ENSRNOP00000026190 | ENSRNOP00000015956 | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity); Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.600 |
Alpi | Ldhc | ENSRNOP00000026190 | ENSRNOP00000017851 | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | L-lactate dehydrogenase C chain; Possible role in sperm motility. | 0.599 |
Alpi | Ntpcr | ENSRNOP00000026190 | ENSRNOP00000026965 | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | Similar to RIKEN cDNA 2310079N02 (Predicted), isoform CRA_a. | 0.900 |
Alpi | Pts | ENSRNOP00000026190 | ENSRNOP00000012434 | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin; Belongs to the PTPS family. | 0.900 |
Alpi | Tpk1 | ENSRNOP00000026190 | ENSRNOP00000044768 | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. | 0.919 |
Gch1 | Alpi | ENSRNOP00000014821 | ENSRNOP00000026190 | GTP cyclohydrolase 1; May positively regulate nitric oxide synthesis in endothelial cells. May be involved in dopamine synthesis (By similarity). May modify pain sensitivity and persistence; Belongs to the GTP cyclohydrolase I family. | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | 0.903 |
Gch1 | Pts | ENSRNOP00000014821 | ENSRNOP00000012434 | GTP cyclohydrolase 1; May positively regulate nitric oxide synthesis in endothelial cells. May be involved in dopamine synthesis (By similarity). May modify pain sensitivity and persistence; Belongs to the GTP cyclohydrolase I family. | 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin; Belongs to the PTPS family. | 0.994 |
Ggt5 | Alpi | ENSRNOP00000076289 | ENSRNOP00000026190 | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | 0.675 |
Ggt5 | Ggt6 | ENSRNOP00000076289 | ENSRNOP00000039691 | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates. | 0.959 |
Ggt5 | Ggt7 | ENSRNOP00000076289 | ENSRNOP00000025315 | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | Glutathione hydrolase 7 heavy chain; Cleaves glutathione conjugates. | 0.955 |
Ggt5 | Got1 | ENSRNOP00000076289 | ENSRNOP00000022309 | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.672 |
Ggt5 | Got2 | ENSRNOP00000076289 | ENSRNOP00000015956 | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity); Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.512 |
Ggt5 | Ldhc | ENSRNOP00000076289 | ENSRNOP00000017851 | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | L-lactate dehydrogenase C chain; Possible role in sperm motility. | 0.586 |
Ggt6 | Alpi | ENSRNOP00000039691 | ENSRNOP00000026190 | Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates. | Intestinal-type alkaline phosphatase 1; Belongs to the alkaline phosphatase family. | 0.737 |
Ggt6 | Ggt5 | ENSRNOP00000039691 | ENSRNOP00000076289 | Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates. | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | 0.959 |