node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aqp2 | Aqp8 | ENSRNOP00000074297 | ENSRNOP00000019939 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis (By similarity). | Aquaporin-8; Forms a water-specific channel; mercury-sensitive. It may have an important role in spermatogenesis, in fertilization, and in the secretion of pancreatic juice and saliva; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.659 |
Aqp2 | Rhbg | ENSRNOP00000074297 | ENSRNOP00000026396 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis (By similarity). | Ammonium transporter Rh type B; Functions as a specific ammonium transporter. | 0.541 |
Aqp2 | Slc12a1 | ENSRNOP00000074297 | ENSRNOP00000073076 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis (By similarity). | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | 0.917 |
Aqp2 | Slc26a4 | ENSRNOP00000074297 | ENSRNOP00000070261 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis (By similarity). | Pendrin; Sodium-independent transporter of chloride and iodide; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.683 |
Aqp2 | Slc4a1 | ENSRNOP00000074297 | ENSRNOP00000028445 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis (By similarity). | Band 3 anion transport protein; Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride- bicarbonate exch [...] | 0.606 |
Aqp2 | Slc9a3 | ENSRNOP00000074297 | ENSRNOP00000020711 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis (By similarity). | Sodium/hydrogen exchanger 3; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.768 |
Aqp6 | Aqp8 | ENSRNOP00000071627 | ENSRNOP00000019939 | Aquaporin-6; Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin-8; Forms a water-specific channel; mercury-sensitive. It may have an important role in spermatogenesis, in fertilization, and in the secretion of pancreatic juice and saliva; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.416 |
Aqp6 | Rhbg | ENSRNOP00000071627 | ENSRNOP00000026396 | Aquaporin-6; Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Ammonium transporter Rh type B; Functions as a specific ammonium transporter. | 0.648 |
Aqp8 | Aqp2 | ENSRNOP00000019939 | ENSRNOP00000074297 | Aquaporin-8; Forms a water-specific channel; mercury-sensitive. It may have an important role in spermatogenesis, in fertilization, and in the secretion of pancreatic juice and saliva; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis (By similarity). | 0.659 |
Aqp8 | Aqp6 | ENSRNOP00000019939 | ENSRNOP00000071627 | Aquaporin-8; Forms a water-specific channel; mercury-sensitive. It may have an important role in spermatogenesis, in fertilization, and in the secretion of pancreatic juice and saliva; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin-6; Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.416 |
Aqp8 | Rhbg | ENSRNOP00000019939 | ENSRNOP00000026396 | Aquaporin-8; Forms a water-specific channel; mercury-sensitive. It may have an important role in spermatogenesis, in fertilization, and in the secretion of pancreatic juice and saliva; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Ammonium transporter Rh type B; Functions as a specific ammonium transporter. | 0.505 |
FAM187A | Rhbg | ENSRNOP00000003892 | ENSRNOP00000026396 | Ig-like V-type domain-containing protein FAM187A. | Ammonium transporter Rh type B; Functions as a specific ammonium transporter. | 0.622 |
Rhbg | Aqp2 | ENSRNOP00000026396 | ENSRNOP00000074297 | Ammonium transporter Rh type B; Functions as a specific ammonium transporter. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis (By similarity). | 0.541 |
Rhbg | Aqp6 | ENSRNOP00000026396 | ENSRNOP00000071627 | Ammonium transporter Rh type B; Functions as a specific ammonium transporter. | Aquaporin-6; Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.648 |
Rhbg | Aqp8 | ENSRNOP00000026396 | ENSRNOP00000019939 | Ammonium transporter Rh type B; Functions as a specific ammonium transporter. | Aquaporin-8; Forms a water-specific channel; mercury-sensitive. It may have an important role in spermatogenesis, in fertilization, and in the secretion of pancreatic juice and saliva; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.505 |
Rhbg | FAM187A | ENSRNOP00000026396 | ENSRNOP00000003892 | Ammonium transporter Rh type B; Functions as a specific ammonium transporter. | Ig-like V-type domain-containing protein FAM187A. | 0.622 |
Rhbg | Rhd | ENSRNOP00000026396 | ENSRNOP00000023187 | Ammonium transporter Rh type B; Functions as a specific ammonium transporter. | Blood group Rh(D) polypeptide; May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. | 0.516 |
Rhbg | Slc12a1 | ENSRNOP00000026396 | ENSRNOP00000073076 | Ammonium transporter Rh type B; Functions as a specific ammonium transporter. | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | 0.553 |
Rhbg | Slc26a4 | ENSRNOP00000026396 | ENSRNOP00000070261 | Ammonium transporter Rh type B; Functions as a specific ammonium transporter. | Pendrin; Sodium-independent transporter of chloride and iodide; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.648 |
Rhbg | Slc4a1 | ENSRNOP00000026396 | ENSRNOP00000028445 | Ammonium transporter Rh type B; Functions as a specific ammonium transporter. | Band 3 anion transport protein; Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride- bicarbonate exch [...] | 0.556 |