Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ctsd | Eea1 | ENSRNOP00000027407 | ENSRNOP00000071305 | Cathepsin D 12 kDa light chain; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | Early endosome antigen 1. | 0.669 |
| Ctsd | Lamp1 | ENSRNOP00000027407 | ENSRNOP00000026580 | Cathepsin D 12 kDa light chain; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | Lysosome-associated membrane glycoprotein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. | 0.975 |
| Ctsd | Lamp2 | ENSRNOP00000027407 | ENSRNOP00000000177 | Cathepsin D 12 kDa light chain; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | Lysosome-associated membrane glycoprotein 2; Plays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and as part of the normal turnover of proteins with a long biological half-live. Binds target proteins, such as GAPDH, and targets them for lysosomal degradation. Plays a role in lysosomal protein degradation in response to starvation. Required for the fusion of autophagosomes with lysosomes during autophagy. Cells that lack LAMP2 express normal levels of VAMP8, but fail to accumulate STX17 on aut [...] | 0.877 |
| Ctsd | Mtor | ENSRNOP00000027407 | ENSRNOP00000014167 | Cathepsin D 12 kDa light chain; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | Serine/threonine-protein kinase mTOR; Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals (By similarity). MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins (By similarity). Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2) (By similarity). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome [...] | 0.484 |
| Depdc5 | Kptn | ENSRNOP00000073874 | ENSRNOP00000002043 | DEP domain-containing 5, GATOR1 subcomplex subunit. | Kaptin (Actin binding protein) (Predicted), isoform CRA_a. | 0.993 |
| Depdc5 | Lamp1 | ENSRNOP00000073874 | ENSRNOP00000026580 | DEP domain-containing 5, GATOR1 subcomplex subunit. | Lysosome-associated membrane glycoprotein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. | 0.945 |
| Depdc5 | Lamp2 | ENSRNOP00000073874 | ENSRNOP00000000177 | DEP domain-containing 5, GATOR1 subcomplex subunit. | Lysosome-associated membrane glycoprotein 2; Plays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and as part of the normal turnover of proteins with a long biological half-live. Binds target proteins, such as GAPDH, and targets them for lysosomal degradation. Plays a role in lysosomal protein degradation in response to starvation. Required for the fusion of autophagosomes with lysosomes during autophagy. Cells that lack LAMP2 express normal levels of VAMP8, but fail to accumulate STX17 on aut [...] | 0.573 |
| Depdc5 | Mtor | ENSRNOP00000073874 | ENSRNOP00000014167 | DEP domain-containing 5, GATOR1 subcomplex subunit. | Serine/threonine-protein kinase mTOR; Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals (By similarity). MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins (By similarity). Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2) (By similarity). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome [...] | 0.758 |
| Depdc5 | Nprl2 | ENSRNOP00000073874 | ENSRNOP00000046410 | DEP domain-containing 5, GATOR1 subcomplex subunit. | Tumor suppressor candidate 4, isoform CRA_a. | 0.999 |
| Depdc5 | Nprl3 | ENSRNOP00000073874 | ENSRNOP00000071482 | DEP domain-containing 5, GATOR1 subcomplex subunit. | NPR3-like, GATOR1 complex subunit. | 0.999 |
| Depdc5 | Rptor | ENSRNOP00000073874 | ENSRNOP00000005337 | DEP domain-containing 5, GATOR1 subcomplex subunit. | Regulatory-associated protein of MTOR, complex 1. | 0.627 |
| Depdc5 | Wdr24 | ENSRNOP00000073874 | ENSRNOP00000026697 | DEP domain-containing 5, GATOR1 subcomplex subunit. | WD repeat domain 24. | 0.999 |
| Eea1 | Ctsd | ENSRNOP00000071305 | ENSRNOP00000027407 | Early endosome antigen 1. | Cathepsin D 12 kDa light chain; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | 0.669 |
| Eea1 | Lamp1 | ENSRNOP00000071305 | ENSRNOP00000026580 | Early endosome antigen 1. | Lysosome-associated membrane glycoprotein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. | 0.963 |
| Eea1 | Lamp2 | ENSRNOP00000071305 | ENSRNOP00000000177 | Early endosome antigen 1. | Lysosome-associated membrane glycoprotein 2; Plays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and as part of the normal turnover of proteins with a long biological half-live. Binds target proteins, such as GAPDH, and targets them for lysosomal degradation. Plays a role in lysosomal protein degradation in response to starvation. Required for the fusion of autophagosomes with lysosomes during autophagy. Cells that lack LAMP2 express normal levels of VAMP8, but fail to accumulate STX17 on aut [...] | 0.862 |
| Kptn | Depdc5 | ENSRNOP00000002043 | ENSRNOP00000073874 | Kaptin (Actin binding protein) (Predicted), isoform CRA_a. | DEP domain-containing 5, GATOR1 subcomplex subunit. | 0.993 |
| Kptn | Lamp1 | ENSRNOP00000002043 | ENSRNOP00000026580 | Kaptin (Actin binding protein) (Predicted), isoform CRA_a. | Lysosome-associated membrane glycoprotein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. | 0.940 |
| Kptn | Lamp2 | ENSRNOP00000002043 | ENSRNOP00000000177 | Kaptin (Actin binding protein) (Predicted), isoform CRA_a. | Lysosome-associated membrane glycoprotein 2; Plays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and as part of the normal turnover of proteins with a long biological half-live. Binds target proteins, such as GAPDH, and targets them for lysosomal degradation. Plays a role in lysosomal protein degradation in response to starvation. Required for the fusion of autophagosomes with lysosomes during autophagy. Cells that lack LAMP2 express normal levels of VAMP8, but fail to accumulate STX17 on aut [...] | 0.507 |
| Kptn | Mtor | ENSRNOP00000002043 | ENSRNOP00000014167 | Kaptin (Actin binding protein) (Predicted), isoform CRA_a. | Serine/threonine-protein kinase mTOR; Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals (By similarity). MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins (By similarity). Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2) (By similarity). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome [...] | 0.534 |
| Kptn | Nprl2 | ENSRNOP00000002043 | ENSRNOP00000046410 | Kaptin (Actin binding protein) (Predicted), isoform CRA_a. | Tumor suppressor candidate 4, isoform CRA_a. | 0.992 |
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