Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bmp8b | Fgf21 | ENSRNOP00000049595 | ENSRNOP00000028490 | Bone morphogenetic protein 8b. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.541 |
| Bmp8b | Fndc5 | ENSRNOP00000049595 | ENSRNOP00000048830 | Bone morphogenetic protein 8b. | Fibronectin type III domain-containing protein 5; [Irisin]: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA (By similarity). | 0.471 |
| Bmp8b | Metrn | ENSRNOP00000049595 | ENSRNOP00000026676 | Bone morphogenetic protein 8b. | Meteorin; Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity). | 0.400 |
| Bmp8b | Ppargc1a | ENSRNOP00000049595 | ENSRNOP00000006071 | Bone morphogenetic protein 8b. | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in [...] | 0.492 |
| Bmp8b | Prdm16 | ENSRNOP00000049595 | ENSRNOP00000064955 | Bone morphogenetic protein 8b. | PR/SET domain 16. | 0.581 |
| Bmp8b | Ucp1 | ENSRNOP00000049595 | ENSRNOP00000004900 | Bone morphogenetic protein 8b. | Mitochondrial brown fat uncoupling protein 1; Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance (By similarity). Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in [...] | 0.673 |
| Fgf21 | Bmp8b | ENSRNOP00000028490 | ENSRNOP00000049595 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Bone morphogenetic protein 8b. | 0.541 |
| Fgf21 | Fndc5 | ENSRNOP00000028490 | ENSRNOP00000048830 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Fibronectin type III domain-containing protein 5; [Irisin]: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA (By similarity). | 0.719 |
| Fgf21 | Metrn | ENSRNOP00000028490 | ENSRNOP00000026676 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Meteorin; Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity). | 0.499 |
| Fgf21 | Mstn | ENSRNOP00000028490 | ENSRNOP00000038159 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. | 0.548 |
| Fgf21 | Ostn | ENSRNOP00000028490 | ENSRNOP00000043654 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Processed Osteocrin; Hormone that acts as a ligand for natriuretic peptide receptor NPR3/NPR-C and promotes bone growth and physical endurance in muscle. Acts as a regulator of osteoblast differentiation and bone growth by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production. Required to enhance physical endurance: induced following physical exercise in muscle and promotes cGMP production, probably by interacting with NPR3/NPR-C. May act as an autocrine and paracrine factor linked [...] | 0.409 |
| Fgf21 | Ppargc1a | ENSRNOP00000028490 | ENSRNOP00000006071 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in [...] | 0.754 |
| Fgf21 | Prdm16 | ENSRNOP00000028490 | ENSRNOP00000064955 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | PR/SET domain 16. | 0.620 |
| Fgf21 | Ucp1 | ENSRNOP00000028490 | ENSRNOP00000004900 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Mitochondrial brown fat uncoupling protein 1; Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance (By similarity). Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in [...] | 0.737 |
| Fndc5 | Bmp8b | ENSRNOP00000048830 | ENSRNOP00000049595 | Fibronectin type III domain-containing protein 5; [Irisin]: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA (By similarity). | Bone morphogenetic protein 8b. | 0.471 |
| Fndc5 | Fgf21 | ENSRNOP00000048830 | ENSRNOP00000028490 | Fibronectin type III domain-containing protein 5; [Irisin]: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA (By similarity). | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.719 |
| Fndc5 | Metrn | ENSRNOP00000048830 | ENSRNOP00000026676 | Fibronectin type III domain-containing protein 5; [Irisin]: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA (By similarity). | Meteorin; Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity). | 0.732 |
| Fndc5 | Mstn | ENSRNOP00000048830 | ENSRNOP00000038159 | Fibronectin type III domain-containing protein 5; [Irisin]: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA (By similarity). | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. | 0.760 |
| Fndc5 | Ostn | ENSRNOP00000048830 | ENSRNOP00000043654 | Fibronectin type III domain-containing protein 5; [Irisin]: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA (By similarity). | Processed Osteocrin; Hormone that acts as a ligand for natriuretic peptide receptor NPR3/NPR-C and promotes bone growth and physical endurance in muscle. Acts as a regulator of osteoblast differentiation and bone growth by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production. Required to enhance physical endurance: induced following physical exercise in muscle and promotes cGMP production, probably by interacting with NPR3/NPR-C. May act as an autocrine and paracrine factor linked [...] | 0.650 |
| Fndc5 | Ppargc1a | ENSRNOP00000048830 | ENSRNOP00000006071 | Fibronectin type III domain-containing protein 5; [Irisin]: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA (By similarity). | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in [...] | 0.786 |
page 1 of 4