| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Apbb1ip | Cadm4 | ENSRNOP00000024272 | ENSRNOP00000026793 | Amyloid beta precursor protein-binding family B member 1-interacting protein. | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | 0.493 |
| C2cd2 | Cadm4 | ENSRNOP00000002209 | ENSRNOP00000026793 | Similar to RIKEN cDNA 5830404H04, isoform CRA_b. | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | 0.538 |
| Cadm4 | Apbb1ip | ENSRNOP00000026793 | ENSRNOP00000024272 | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | Amyloid beta precursor protein-binding family B member 1-interacting protein. | 0.493 |
| Cadm4 | C2cd2 | ENSRNOP00000026793 | ENSRNOP00000002209 | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | Similar to RIKEN cDNA 5830404H04, isoform CRA_b. | 0.538 |
| Cadm4 | Cntnap1 | ENSRNOP00000026793 | ENSRNOP00000027505 | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | Contactin-associated protein 1; Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells. | 0.650 |
| Cadm4 | Enpp5 | ENSRNOP00000026793 | ENSRNOP00000013703 | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | Ectonucleotide pyrophosphatase/phosphodiesterase family member 5; Can hydrolyze NAD but cannot hydrolyze nucleotide di- and triphosphates (By similarity). May play a role in neuronal cell communication. Lacks nucleotide pyrophosphatase and lysopholipase D activity in vitro. | 0.522 |
| Cadm4 | Fdps | ENSRNOP00000026793 | ENSRNOP00000031191 | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | Farnesyl pyrophosphate synthase; Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (By similarity); Belongs to the FPP/GG [...] | 0.476 |
| Cadm4 | Gldn | ENSRNOP00000026793 | ENSRNOP00000029833 | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | Gliomedin shedded ectodomain; Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of [...] | 0.513 |
| Cadm4 | Hepacam2 | ENSRNOP00000026793 | ENSRNOP00000012995 | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | HEPACAM family member 2. | 0.505 |
| Cadm4 | Lgi4 | ENSRNOP00000026793 | ENSRNOP00000028632 | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | Leucine-rich repeat LGI family, member 4. | 0.466 |
| Cadm4 | Lrrc4 | ENSRNOP00000026793 | ENSRNOP00000010673 | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | Leucine-rich repeat-containing protein 4; Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays an important role for auditory synaptic responses. Involved in the suppression of glioma. | 0.494 |
| Cadm4 | Nfasc | ENSRNOP00000026793 | ENSRNOP00000057594 | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | Neurofascin; Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions. Isoform 2/isoform 3 may be responsible for mediating and signaling axon-glial interaction during the early stages of myelination; Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family. | 0.562 |
| Cntnap1 | Cadm4 | ENSRNOP00000027505 | ENSRNOP00000026793 | Contactin-associated protein 1; Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells. | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | 0.650 |
| Cntnap1 | Gldn | ENSRNOP00000027505 | ENSRNOP00000029833 | Contactin-associated protein 1; Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells. | Gliomedin shedded ectodomain; Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of [...] | 0.754 |
| Cntnap1 | Lgi4 | ENSRNOP00000027505 | ENSRNOP00000028632 | Contactin-associated protein 1; Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells. | Leucine-rich repeat LGI family, member 4. | 0.463 |
| Cntnap1 | Nfasc | ENSRNOP00000027505 | ENSRNOP00000057594 | Contactin-associated protein 1; Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells. | Neurofascin; Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions. Isoform 2/isoform 3 may be responsible for mediating and signaling axon-glial interaction during the early stages of myelination; Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family. | 0.992 |
| Enpp5 | Cadm4 | ENSRNOP00000013703 | ENSRNOP00000026793 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 5; Can hydrolyze NAD but cannot hydrolyze nucleotide di- and triphosphates (By similarity). May play a role in neuronal cell communication. Lacks nucleotide pyrophosphatase and lysopholipase D activity in vitro. | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | 0.522 |
| Enpp5 | Lrrc4 | ENSRNOP00000013703 | ENSRNOP00000010673 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 5; Can hydrolyze NAD but cannot hydrolyze nucleotide di- and triphosphates (By similarity). May play a role in neuronal cell communication. Lacks nucleotide pyrophosphatase and lysopholipase D activity in vitro. | Leucine-rich repeat-containing protein 4; Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays an important role for auditory synaptic responses. Involved in the suppression of glioma. | 0.625 |
| Fdps | Cadm4 | ENSRNOP00000031191 | ENSRNOP00000026793 | Farnesyl pyrophosphate synthase; Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (By similarity); Belongs to the FPP/GG [...] | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | 0.476 |
| Gldn | Cadm4 | ENSRNOP00000029833 | ENSRNOP00000026793 | Gliomedin shedded ectodomain; Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of [...] | Cell adhesion molecule 4; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity); Belongs to the nectin family. | 0.513 |
