node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Coasy | Mlx | ENSRNOP00000027061 | ENSRNOP00000027116 | Coenzyme A synthase. | MAX-like protein X, isoform CRA_a. | 0.438 |
Coasy | Pank4 | ENSRNOP00000027061 | ENSRNOP00000019028 | Coenzyme A synthase. | 4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their co [...] | 0.841 |
Coasy | Ppcs | ENSRNOP00000027061 | ENSRNOP00000011392 | Coenzyme A synthase. | Phosphopantothenoylcysteine synthetase. | 0.991 |
Mlx | Coasy | ENSRNOP00000027116 | ENSRNOP00000027061 | MAX-like protein X, isoform CRA_a. | Coenzyme A synthase. | 0.438 |
Mlx | Mlxip | ENSRNOP00000027116 | ENSRNOP00000001690 | MAX-like protein X, isoform CRA_a. | MLX-interacting protein. | 0.985 |
Mlx | Mnt | ENSRNOP00000027116 | ENSRNOP00000075865 | MAX-like protein X, isoform CRA_a. | MAX network transcriptional repressor. | 0.600 |
Mlx | Mxd1 | ENSRNOP00000027116 | ENSRNOP00000023856 | MAX-like protein X, isoform CRA_a. | Max dimerization protein 1. | 0.421 |
Mlx | Mxd4 | ENSRNOP00000027116 | ENSRNOP00000067906 | MAX-like protein X, isoform CRA_a. | Max dimerization protein 4. | 0.531 |
Mlx | Ogt | ENSRNOP00000027116 | ENSRNOP00000072791 | MAX-like protein X, isoform CRA_a. | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N- acetylglucosamine (O-GlcNAc). Has 3 distinct KM values for UDP-GlcNAc; GlcNAc concentration modulates its affinity for different substrates. Glycosylates a large and diverse number of proteins including histone H2B, AKT1, EZH2, PFKL, KMT2E/MLL5, MAPT/TAU and HCFC1. Can regulate their cellular processes via cross-ta [...] | 0.900 |
Mlx | Pank4 | ENSRNOP00000027116 | ENSRNOP00000019028 | MAX-like protein X, isoform CRA_a. | 4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their co [...] | 0.553 |
Mlx | Ppargc1b | ENSRNOP00000027116 | ENSRNOP00000023661 | MAX-like protein X, isoform CRA_a. | Peroxisome proliferator-activated receptor gamma coactivator 1-beta; Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be part of the pathways regulating the elevation of gluconeogenesis, beta-oxidation of fatty [...] | 0.900 |
Mlx | Ppcs | ENSRNOP00000027116 | ENSRNOP00000011392 | MAX-like protein X, isoform CRA_a. | Phosphopantothenoylcysteine synthetase. | 0.410 |
Mlx | Ptpa | ENSRNOP00000027116 | ENSRNOP00000024914 | MAX-like protein X, isoform CRA_a. | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | 0.900 |
Mlxip | Mlx | ENSRNOP00000001690 | ENSRNOP00000027116 | MLX-interacting protein. | MAX-like protein X, isoform CRA_a. | 0.985 |
Mlxip | Mxd1 | ENSRNOP00000001690 | ENSRNOP00000023856 | MLX-interacting protein. | Max dimerization protein 1. | 0.591 |
Mlxip | Mxd4 | ENSRNOP00000001690 | ENSRNOP00000067906 | MLX-interacting protein. | Max dimerization protein 4. | 0.642 |
Mlxip | Ogt | ENSRNOP00000001690 | ENSRNOP00000072791 | MLX-interacting protein. | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N- acetylglucosamine (O-GlcNAc). Has 3 distinct KM values for UDP-GlcNAc; GlcNAc concentration modulates its affinity for different substrates. Glycosylates a large and diverse number of proteins including histone H2B, AKT1, EZH2, PFKL, KMT2E/MLL5, MAPT/TAU and HCFC1. Can regulate their cellular processes via cross-ta [...] | 0.920 |
Mlxip | Ppargc1b | ENSRNOP00000001690 | ENSRNOP00000023661 | MLX-interacting protein. | Peroxisome proliferator-activated receptor gamma coactivator 1-beta; Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be part of the pathways regulating the elevation of gluconeogenesis, beta-oxidation of fatty [...] | 0.915 |
Mlxip | Ptpa | ENSRNOP00000001690 | ENSRNOP00000024914 | MLX-interacting protein. | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | 0.900 |
Mnt | Mlx | ENSRNOP00000075865 | ENSRNOP00000027116 | MAX network transcriptional repressor. | MAX-like protein X, isoform CRA_a. | 0.600 |