| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Fxn | Iscu | ENSRNOP00000020412 | ENSRNOP00000000890 | Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity). | Similar to nitrogen fixation cluster-like (Predicted), isoform CRA_b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.998 |
| Fxn | Nfu1 | ENSRNOP00000020412 | ENSRNOP00000024884 | Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity). | Histone cell cycle regulation defective interacting protein 5 (Predicted), isoform CRA_a. | 0.805 |
| Fxn | Scly | ENSRNOP00000020412 | ENSRNOP00000027220 | Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity). | Selenocysteine lyase; Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. | 0.908 |
| Iscu | Fxn | ENSRNOP00000000890 | ENSRNOP00000020412 | Similar to nitrogen fixation cluster-like (Predicted), isoform CRA_b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity). | 0.998 |
| Iscu | Nfu1 | ENSRNOP00000000890 | ENSRNOP00000024884 | Similar to nitrogen fixation cluster-like (Predicted), isoform CRA_b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Histone cell cycle regulation defective interacting protein 5 (Predicted), isoform CRA_a. | 0.940 |
| Iscu | Scly | ENSRNOP00000000890 | ENSRNOP00000027220 | Similar to nitrogen fixation cluster-like (Predicted), isoform CRA_b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Selenocysteine lyase; Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. | 0.986 |
| Nfu1 | Fxn | ENSRNOP00000024884 | ENSRNOP00000020412 | Histone cell cycle regulation defective interacting protein 5 (Predicted), isoform CRA_a. | Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity). | 0.805 |
| Nfu1 | Iscu | ENSRNOP00000024884 | ENSRNOP00000000890 | Histone cell cycle regulation defective interacting protein 5 (Predicted), isoform CRA_a. | Similar to nitrogen fixation cluster-like (Predicted), isoform CRA_b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.940 |
| Nfu1 | Scly | ENSRNOP00000024884 | ENSRNOP00000027220 | Histone cell cycle regulation defective interacting protein 5 (Predicted), isoform CRA_a. | Selenocysteine lyase; Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. | 0.855 |
| Pstk | Scly | ENSRNOP00000027967 | ENSRNOP00000027220 | Phosphoseryl-tRNA kinase. | Selenocysteine lyase; Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. | 0.747 |
| Pstk | Selenom | ENSRNOP00000027967 | ENSRNOP00000071242 | Phosphoseryl-tRNA kinase. | Selenoprotein M. | 0.549 |
| Pstk | Sephs1 | ENSRNOP00000027967 | ENSRNOP00000024697 | Phosphoseryl-tRNA kinase. | Selenophosphate synthetase 1, isoform CRA_a. | 0.772 |
| Pstk | Sepsecs | ENSRNOP00000027967 | ENSRNOP00000065651 | Phosphoseryl-tRNA kinase. | O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. | 0.994 |
| Pstk | Txnrd1 | ENSRNOP00000027967 | ENSRNOP00000013612 | Phosphoseryl-tRNA kinase. | Thioredoxin reductase 1, cytoplasmic. | 0.475 |
| Pstk | Txnrd2 | ENSRNOP00000027967 | ENSRNOP00000002593 | Phosphoseryl-tRNA kinase. | Thioredoxin reductase 2, mitochondrial; Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis (By similarity). Maintains mitochondrial thioredoxin in a reduced state. May play a role in redox-regulated cell signaling. | 0.456 |
| Scly | Fxn | ENSRNOP00000027220 | ENSRNOP00000020412 | Selenocysteine lyase; Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. | Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity). | 0.908 |
| Scly | Iscu | ENSRNOP00000027220 | ENSRNOP00000000890 | Selenocysteine lyase; Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. | Similar to nitrogen fixation cluster-like (Predicted), isoform CRA_b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.986 |
| Scly | Nfu1 | ENSRNOP00000027220 | ENSRNOP00000024884 | Selenocysteine lyase; Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. | Histone cell cycle regulation defective interacting protein 5 (Predicted), isoform CRA_a. | 0.855 |
| Scly | Pstk | ENSRNOP00000027220 | ENSRNOP00000027967 | Selenocysteine lyase; Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. | Phosphoseryl-tRNA kinase. | 0.747 |
| Scly | Selenom | ENSRNOP00000027220 | ENSRNOP00000071242 | Selenocysteine lyase; Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. | Selenoprotein M. | 0.828 |