node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Eno1 | Eno3 | ENSRNOP00000073191 | ENSRNOP00000005612 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | 0.733 |
Eno1 | Eno4 | ENSRNOP00000073191 | ENSRNOP00000063070 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. | Similar to enolase (46.6 kD) (2J223) (Predicted). | 0.659 |
Eno1 | Gpi | ENSRNOP00000073191 | ENSRNOP00000029515 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). Belongs to the GPI family. | 0.986 |
Eno1 | LOC100911625 | ENSRNOP00000073191 | ENSRNOP00000005535 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. | Gamma-enolase; Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium- dependent manner, to cultured neocortical neurons and promotes cell survival; Belongs to the enolase family. | 0.826 |
Eno1 | Ldha | ENSRNOP00000073191 | ENSRNOP00000017468 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. | L-lactate dehydrogenase A chain. | 0.842 |
Eno1 | Ldhb | ENSRNOP00000073191 | ENSRNOP00000017965 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. | L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. | 0.782 |
Eno1 | Ldhc | ENSRNOP00000073191 | ENSRNOP00000017851 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. | L-lactate dehydrogenase C chain; Possible role in sperm motility. | 0.575 |
Eno1 | Pc | ENSRNOP00000073191 | ENSRNOP00000068757 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. | Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate. | 0.484 |
Eno1 | Pck1 | ENSRNOP00000073191 | ENSRNOP00000030913 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. | Phosphoenolpyruvate carboxykinase, cytosolic [GTP]; Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate. | 0.950 |
Eno1 | Pklr | ENSRNOP00000073191 | ENSRNOP00000027700 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. | Pyruvate kinase PKLR; Plays a key role in glycolysis. | 0.981 |
Eno3 | Eno1 | ENSRNOP00000005612 | ENSRNOP00000073191 | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. | 0.733 |
Eno3 | Eno4 | ENSRNOP00000005612 | ENSRNOP00000063070 | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | Similar to enolase (46.6 kD) (2J223) (Predicted). | 0.647 |
Eno3 | Gpi | ENSRNOP00000005612 | ENSRNOP00000029515 | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). Belongs to the GPI family. | 0.966 |
Eno3 | LOC100911625 | ENSRNOP00000005612 | ENSRNOP00000005535 | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | Gamma-enolase; Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium- dependent manner, to cultured neocortical neurons and promotes cell survival; Belongs to the enolase family. | 0.817 |
Eno3 | Ldha | ENSRNOP00000005612 | ENSRNOP00000017468 | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | L-lactate dehydrogenase A chain. | 0.659 |
Eno3 | Ldhb | ENSRNOP00000005612 | ENSRNOP00000017965 | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. | 0.602 |
Eno3 | Ldhc | ENSRNOP00000005612 | ENSRNOP00000017851 | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | L-lactate dehydrogenase C chain; Possible role in sperm motility. | 0.525 |
Eno3 | Pck1 | ENSRNOP00000005612 | ENSRNOP00000030913 | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | Phosphoenolpyruvate carboxykinase, cytosolic [GTP]; Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate. | 0.945 |
Eno3 | Pklr | ENSRNOP00000005612 | ENSRNOP00000027700 | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | Pyruvate kinase PKLR; Plays a key role in glycolysis. | 0.979 |
Eno4 | Eno1 | ENSRNOP00000063070 | ENSRNOP00000073191 | Similar to enolase (46.6 kD) (2J223) (Predicted). | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. | 0.659 |