node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gale | Pin1 | ENSRNOP00000013322 | ENSRNOP00000027819 | UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...] | Peptidyl-prolyl cis-trans isomerase. | 0.738 |
Gphn | Pin1 | ENSRNOP00000064099 | ENSRNOP00000027819 | Molybdopterin molybdenumtransferase; Microtubule-associated protein involved in membrane protein- cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released ; In the N-terminal section; belongs to the MoaB/Mog family. | Peptidyl-prolyl cis-trans isomerase. | 0.726 |
Hipk2 | M0R497_RAT | ENSRNOP00000060564 | ENSRNOP00000064177 | Homeodomain interacting protein kinase 2 (Predicted), isoform CRA_a. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.660 |
Hipk2 | Pin1 | ENSRNOP00000060564 | ENSRNOP00000027819 | Homeodomain interacting protein kinase 2 (Predicted), isoform CRA_a. | Peptidyl-prolyl cis-trans isomerase. | 0.953 |
Hipk2 | Tp53 | ENSRNOP00000060564 | ENSRNOP00000074031 | Homeodomain interacting protein kinase 2 (Predicted), isoform CRA_a. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.990 |
Irf3 | Pin1 | ENSRNOP00000027786 | ENSRNOP00000027819 | Interferon regulatory factor 3, isoform CRA_c. | Peptidyl-prolyl cis-trans isomerase. | 0.959 |
Irf3 | Tp53 | ENSRNOP00000027786 | ENSRNOP00000074031 | Interferon regulatory factor 3, isoform CRA_c. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.533 |
M0R497_RAT | Hipk2 | ENSRNOP00000064177 | ENSRNOP00000060564 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Homeodomain interacting protein kinase 2 (Predicted), isoform CRA_a. | 0.660 |
M0R497_RAT | Pin1 | ENSRNOP00000064177 | ENSRNOP00000027819 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Peptidyl-prolyl cis-trans isomerase. | 0.806 |
Ncf1 | Ncf4 | ENSRNOP00000002028 | ENSRNOP00000009544 | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | Similar to neutrophil cytosolic factor 4, isoform CRA_a. | 0.999 |
Ncf1 | Pin1 | ENSRNOP00000002028 | ENSRNOP00000027819 | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | Peptidyl-prolyl cis-trans isomerase. | 0.900 |
Ncf1 | Tp53 | ENSRNOP00000002028 | ENSRNOP00000074031 | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.454 |
Ncf4 | Ncf1 | ENSRNOP00000009544 | ENSRNOP00000002028 | Similar to neutrophil cytosolic factor 4, isoform CRA_a. | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | 0.999 |
Ncf4 | Pin1 | ENSRNOP00000009544 | ENSRNOP00000027819 | Similar to neutrophil cytosolic factor 4, isoform CRA_a. | Peptidyl-prolyl cis-trans isomerase. | 0.900 |
Pin1 | Gale | ENSRNOP00000027819 | ENSRNOP00000013322 | Peptidyl-prolyl cis-trans isomerase. | UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...] | 0.738 |
Pin1 | Gphn | ENSRNOP00000027819 | ENSRNOP00000064099 | Peptidyl-prolyl cis-trans isomerase. | Molybdopterin molybdenumtransferase; Microtubule-associated protein involved in membrane protein- cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released ; In the N-terminal section; belongs to the MoaB/Mog family. | 0.726 |
Pin1 | Hipk2 | ENSRNOP00000027819 | ENSRNOP00000060564 | Peptidyl-prolyl cis-trans isomerase. | Homeodomain interacting protein kinase 2 (Predicted), isoform CRA_a. | 0.953 |
Pin1 | Irf3 | ENSRNOP00000027819 | ENSRNOP00000027786 | Peptidyl-prolyl cis-trans isomerase. | Interferon regulatory factor 3, isoform CRA_c. | 0.959 |
Pin1 | M0R497_RAT | ENSRNOP00000027819 | ENSRNOP00000064177 | Peptidyl-prolyl cis-trans isomerase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.806 |
Pin1 | Ncf1 | ENSRNOP00000027819 | ENSRNOP00000002028 | Peptidyl-prolyl cis-trans isomerase. | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | 0.900 |