| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bmyc | M0R497_RAT | ENSRNOP00000059721 | ENSRNOP00000064177 | Protein B-Myc; Seems to act as an inhibitor of cellular proliferation. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.725 |
| Bmyc | Pin1 | ENSRNOP00000059721 | ENSRNOP00000027819 | Protein B-Myc; Seems to act as an inhibitor of cellular proliferation. | Peptidyl-prolyl cis-trans isomerase. | 0.818 |
| Bmyc | Plk1 | ENSRNOP00000059721 | ENSRNOP00000025629 | Protein B-Myc; Seems to act as an inhibitor of cellular proliferation. | Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...] | 0.792 |
| Bmyc | Pml | ENSRNOP00000059721 | ENSRNOP00000042091 | Protein B-Myc; Seems to act as an inhibitor of cellular proliferation. | Promyelocytic leukemia. | 0.814 |
| Bmyc | Polr2a | ENSRNOP00000059721 | ENSRNOP00000061492 | Protein B-Myc; Seems to act as an inhibitor of cellular proliferation. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.734 |
| Bmyc | Tp53 | ENSRNOP00000059721 | ENSRNOP00000074031 | Protein B-Myc; Seems to act as an inhibitor of cellular proliferation. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.784 |
| Irf3 | Pin1 | ENSRNOP00000027786 | ENSRNOP00000027819 | Interferon regulatory factor 3, isoform CRA_c. | Peptidyl-prolyl cis-trans isomerase. | 0.963 |
| Irf3 | Tp53 | ENSRNOP00000027786 | ENSRNOP00000074031 | Interferon regulatory factor 3, isoform CRA_c. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.514 |
| M0R497_RAT | Bmyc | ENSRNOP00000064177 | ENSRNOP00000059721 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Protein B-Myc; Seems to act as an inhibitor of cellular proliferation. | 0.725 |
| M0R497_RAT | Pin1 | ENSRNOP00000064177 | ENSRNOP00000027819 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Peptidyl-prolyl cis-trans isomerase. | 0.833 |
| M0R497_RAT | Plk1 | ENSRNOP00000064177 | ENSRNOP00000025629 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...] | 0.766 |
| M0R497_RAT | Pml | ENSRNOP00000064177 | ENSRNOP00000042091 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Promyelocytic leukemia. | 0.797 |
| M0R497_RAT | Polr2d | ENSRNOP00000064177 | ENSRNOP00000021738 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Polymerase (RNA) II (DNA directed) polypeptide D (Predicted). | 0.475 |
| Mapt | Pin1 | ENSRNOP00000040951 | ENSRNOP00000027819 | Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabili [...] | Peptidyl-prolyl cis-trans isomerase. | 0.921 |
| Mapt | Tp53 | ENSRNOP00000040951 | ENSRNOP00000074031 | Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabili [...] | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.414 |
| Pin1 | Bmyc | ENSRNOP00000027819 | ENSRNOP00000059721 | Peptidyl-prolyl cis-trans isomerase. | Protein B-Myc; Seems to act as an inhibitor of cellular proliferation. | 0.818 |
| Pin1 | Irf3 | ENSRNOP00000027819 | ENSRNOP00000027786 | Peptidyl-prolyl cis-trans isomerase. | Interferon regulatory factor 3, isoform CRA_c. | 0.963 |
| Pin1 | M0R497_RAT | ENSRNOP00000027819 | ENSRNOP00000064177 | Peptidyl-prolyl cis-trans isomerase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.833 |
| Pin1 | Mapt | ENSRNOP00000027819 | ENSRNOP00000040951 | Peptidyl-prolyl cis-trans isomerase. | Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabili [...] | 0.921 |
| Pin1 | Plk1 | ENSRNOP00000027819 | ENSRNOP00000025629 | Peptidyl-prolyl cis-trans isomerase. | Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...] | 0.848 |
