STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slc6a15Sodium-dependent neutral amino acid transporter B(0)AT2; Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for methionine and for the branched- chain amino acids, particularly leucine, valine and isoleucine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity). (729 aa)    
Predicted Functional Partners:
Slc38a6
Probable sodium-coupled neutral amino acid transporter 6; Probable sodium-dependent amino acid/proton antiporter, could be a neuronal transporter for glutamate. Belongs to the amino acid/polyamine transporter 2 family.
   
  
 0.574
Slc1a5
Amino acid transporter.
  
  
 0.512
Vom2r9
Vomeronasal 2 receptor, 9.
   
  
 0.511
Slc44a5
Solute carrier family 44, member 5; Belongs to the CTL (choline transporter-like) family.
   
  
 0.492
Slc38a8
Solute carrier family 38, member 8.
   
  
 0.489
Synpr
Synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein.
   
 
 0.483
Slc38a11
Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter.
   
  
 0.477
Slc3a1
Neutral and basic amino acid transport protein rBAT; Involved in the high-affinity sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney proximal tubule.
   
 
 0.474
Rgs9
Regulator of G-protein signaling 9; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to GNAT1. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).
   
  
 0.456
Slc30a9
Solute carrier family 30 member 9.
  
  
 0.435
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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