node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adgrl4 | Dll4 | ENSRNOP00000071560 | ENSRNOP00000018970 | Adhesion G protein-coupled receptor L4; Endothelial orphan receptor that acts as a key regulator of angiogenesis. | Delta-like protein 4; Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity). | 0.658 |
Adgrl4 | Emcn | ENSRNOP00000071560 | ENSRNOP00000033031 | Adhesion G protein-coupled receptor L4; Endothelial orphan receptor that acts as a key regulator of angiogenesis. | Endomucin; Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. | 0.771 |
Adgrl4 | Kdr | ENSRNOP00000071560 | ENSRNOP00000066886 | Adhesion G protein-coupled receptor L4; Endothelial orphan receptor that acts as a key regulator of angiogenesis. | Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular grow [...] | 0.654 |
Adgrl4 | Sox18 | ENSRNOP00000071560 | ENSRNOP00000021790 | Adhesion G protein-coupled receptor L4; Endothelial orphan receptor that acts as a key regulator of angiogenesis. | SRY (Sex determining region Y)-box 18. | 0.492 |
Adgrl4 | Tek | ENSRNOP00000071560 | ENSRNOP00000036086 | Adhesion G protein-coupled receptor L4; Endothelial orphan receptor that acts as a key regulator of angiogenesis. | Endothelial-specific receptor tyrosine kinase. | 0.527 |
Cdh5 | Dll4 | ENSRNOP00000017983 | ENSRNOP00000018970 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Delta-like protein 4; Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity). | 0.684 |
Cdh5 | Emcn | ENSRNOP00000017983 | ENSRNOP00000033031 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Endomucin; Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. | 0.737 |
Cdh5 | Kdr | ENSRNOP00000017983 | ENSRNOP00000066886 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular grow [...] | 0.994 |
Cdh5 | Lyve1 | ENSRNOP00000017983 | ENSRNOP00000036731 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Extracellular link domain-containing 1 (Predicted). | 0.643 |
Cdh5 | Sox18 | ENSRNOP00000017983 | ENSRNOP00000021790 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | SRY (Sex determining region Y)-box 18. | 0.715 |
Cdh5 | Tek | ENSRNOP00000017983 | ENSRNOP00000036086 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Endothelial-specific receptor tyrosine kinase. | 0.877 |
Dll4 | Adgrl4 | ENSRNOP00000018970 | ENSRNOP00000071560 | Delta-like protein 4; Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity). | Adhesion G protein-coupled receptor L4; Endothelial orphan receptor that acts as a key regulator of angiogenesis. | 0.658 |
Dll4 | Cdh5 | ENSRNOP00000018970 | ENSRNOP00000017983 | Delta-like protein 4; Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity). | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | 0.684 |
Dll4 | Emcn | ENSRNOP00000018970 | ENSRNOP00000033031 | Delta-like protein 4; Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity). | Endomucin; Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. | 0.688 |
Dll4 | Kdr | ENSRNOP00000018970 | ENSRNOP00000066886 | Delta-like protein 4; Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity). | Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular grow [...] | 0.757 |
Dll4 | Lyve1 | ENSRNOP00000018970 | ENSRNOP00000036731 | Delta-like protein 4; Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity). | Extracellular link domain-containing 1 (Predicted). | 0.461 |
Dll4 | Sox18 | ENSRNOP00000018970 | ENSRNOP00000021790 | Delta-like protein 4; Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity). | SRY (Sex determining region Y)-box 18. | 0.518 |
Dll4 | Tek | ENSRNOP00000018970 | ENSRNOP00000036086 | Delta-like protein 4; Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity). | Endothelial-specific receptor tyrosine kinase. | 0.690 |
Emcn | Adgrl4 | ENSRNOP00000033031 | ENSRNOP00000071560 | Endomucin; Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. | Adhesion G protein-coupled receptor L4; Endothelial orphan receptor that acts as a key regulator of angiogenesis. | 0.771 |
Emcn | Cdh5 | ENSRNOP00000033031 | ENSRNOP00000017983 | Endomucin; Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | 0.737 |