STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hoxb7Homeobox protein Hox-B7; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (219 aa)    
Predicted Functional Partners:
Hoxb6
Similar to homeotic protein Hox 2.2-mouse (Predicted).
   
 
0.973
Hoxb5
Similar to homeotic protein Hox B5-mouse (Predicted).
   
 
0.927
Xrcc6
X-ray repair cross-complementing 6.
    
 
 0.817
Ghrl
Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation; Belongs to the motilin family.
   
  
 0.815
Hoxc6
Homeo box C6.
   
 
0.812
Hoxb8
Homeobox protein Hox-B8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
   
 
0.806
Xrcc5
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
    
 
 0.798
Prkdc
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
    
 
 0.789
Pbx2
Pre-B-cell leukemia transcription factor 2.
    
 
 0.750
Hoxd4
Homeo box D4 (Predicted), isoform CRA_a.
   
 
0.747
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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