STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ankrd46Ankyrin repeat domain-containing protein 46. (228 aa)    
Predicted Functional Partners:
Lrch4
Leucine-rich repeats and calponin homology domain-containing 4.
   
 
 0.694
Agfg2
ArfGAP with FG repeats 2.
   
  
 0.640
LOC100912259
Single-pass membrane and coiled-coil domain-containing protein 3.
      
 0.634
Smco3
Single-pass membrane and coiled-coil domain-containing protein 3.
      
 0.634
Zfp420
Zinc finger protein 420.
    
 
 0.631
Spryd4
SPRY domain-containing protein 4.
    
 
 0.593
Asz1
Ankyrin repeat, SAM and basic leucine zipper domain-containing 1.
  
 
 
 0.591
Acap1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1.
    
 
 0.577
Cul2
Cullin 2; Belongs to the cullin family.
    
 
 0.575
Gnb2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.541
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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