Sit1 protein (Rattus norvegicus) - STRING interaction network

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Sit1

Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells. (178 aa)

Predicted Functional Partners:

Cd7

0.729

Ly6d

0.570

Acat2l1

0.496

RT1-T24-4

0.466

Kifap3

0.448

Trat1

0.442

Slamf9

0.441

Tmco2

0.409

Arl10

0.409

Cyp3a18

0.408

Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acat2l1	Sit1	ENSRNOP00000068312	ENSRNOP00000036171	Acetyl-CoA acetyltransferase, cytosolic; Involved in the biosynthetic pathway of cholesterol.	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	0.496
Arl10	Cd7	ENSRNOP00000066910	ENSRNOP00000051817	ADP-ribosylation factor-like 10, isoform CRA_a.	CD7 antigen (Predicted).	0.497
Arl10	Sit1	ENSRNOP00000066910	ENSRNOP00000036171	ADP-ribosylation factor-like 10, isoform CRA_a.	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	0.409
Cd7	Arl10	ENSRNOP00000051817	ENSRNOP00000066910	CD7 antigen (Predicted).	ADP-ribosylation factor-like 10, isoform CRA_a.	0.497
Cd7	Sit1	ENSRNOP00000051817	ENSRNOP00000036171	CD7 antigen (Predicted).	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	0.729
Cyp3a18	Sit1	ENSRNOP00000001285	ENSRNOP00000036171	Cytochrome P450 3A18; Catalyzes 16-beta- and 6-alpha-hydroxylations of testosterone.	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	0.408
Kifap3	Sit1	ENSRNOP00000071523	ENSRNOP00000036171	Kinesin-associated protein 3.	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	0.448
Ly6d	Sit1	ENSRNOP00000031140	ENSRNOP00000036171	Lymphocyte antigen 6 complex, locus D (Predicted).	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	0.570
RT1-T24-4	Sit1	ENSRNOP00000043387	ENSRNOP00000036171	Histocompatibility 2, T region locus 24; Belongs to the MHC class I family.	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	0.466
Sit1	Acat2l1	ENSRNOP00000036171	ENSRNOP00000068312	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	Acetyl-CoA acetyltransferase, cytosolic; Involved in the biosynthetic pathway of cholesterol.	0.496
Sit1	Arl10	ENSRNOP00000036171	ENSRNOP00000066910	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	ADP-ribosylation factor-like 10, isoform CRA_a.	0.409
Sit1	Cd7	ENSRNOP00000036171	ENSRNOP00000051817	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	CD7 antigen (Predicted).	0.729
Sit1	Cyp3a18	ENSRNOP00000036171	ENSRNOP00000001285	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	Cytochrome P450 3A18; Catalyzes 16-beta- and 6-alpha-hydroxylations of testosterone.	0.408
Sit1	Kifap3	ENSRNOP00000036171	ENSRNOP00000071523	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	Kinesin-associated protein 3.	0.448
Sit1	Ly6d	ENSRNOP00000036171	ENSRNOP00000031140	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	Lymphocyte antigen 6 complex, locus D (Predicted).	0.570
Sit1	RT1-T24-4	ENSRNOP00000036171	ENSRNOP00000043387	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	Histocompatibility 2, T region locus 24; Belongs to the MHC class I family.	0.466
Sit1	Slamf9	ENSRNOP00000036171	ENSRNOP00000010594	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	SLAM family member 9 (Predicted).	0.441
Sit1	Tmco2	ENSRNOP00000036171	ENSRNOP00000016492	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	Transmembrane and coiled-coil domains 2.	0.409
Sit1	Trat1	ENSRNOP00000036171	ENSRNOP00000056668	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	T cell receptor-associated transmembrane adaptor 1.	0.442
Slamf9	Sit1	ENSRNOP00000010594	ENSRNOP00000036171	SLAM family member 9 (Predicted).	Signaling threshold-regulating transmembrane adapter 1; Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.	0.441

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