node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aga | Fuca1 | ENSRNOP00000000120 | ENSRNOP00000012455 | N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase; Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. Belongs to the Ntn-hydrolase family. | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | 0.405 |
Aga | Hexa | ENSRNOP00000000120 | ENSRNOP00000013747 | N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase; Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. Belongs to the Ntn-hydrolase family. | Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.539 |
Aga | Hexb | ENSRNOP00000000120 | ENSRNOP00000044480 | N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase; Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. Belongs to the Ntn-hydrolase family. | Beta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.535 |
Cyb5d2 | Gm2a | ENSRNOP00000038452 | ENSRNOP00000071876 | Neuferricin; Heme-binding protein which promotes neuronal but not astrocyte differentiation; Belongs to the cytochrome b5 family. MAPR subfamily. | GM2 ganglioside activator protein. | 0.685 |
Cyb5d2 | Hexa | ENSRNOP00000038452 | ENSRNOP00000013747 | Neuferricin; Heme-binding protein which promotes neuronal but not astrocyte differentiation; Belongs to the cytochrome b5 family. MAPR subfamily. | Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.569 |
Cyb5d2 | Hexb | ENSRNOP00000038452 | ENSRNOP00000044480 | Neuferricin; Heme-binding protein which promotes neuronal but not astrocyte differentiation; Belongs to the cytochrome b5 family. MAPR subfamily. | Beta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.495 |
Fuca1 | Aga | ENSRNOP00000012455 | ENSRNOP00000000120 | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase; Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. Belongs to the Ntn-hydrolase family. | 0.405 |
Fuca1 | Glb1 | ENSRNOP00000012455 | ENSRNOP00000013632 | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | Beta-galactosidase. | 0.825 |
Fuca1 | Hexa | ENSRNOP00000012455 | ENSRNOP00000013747 | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.655 |
Fuca1 | Hexb | ENSRNOP00000012455 | ENSRNOP00000044480 | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | Beta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.519 |
Fuca1 | Naga | ENSRNOP00000012455 | ENSRNOP00000060590 | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | Alpha-N-acetylgalactosaminidase; Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids (By similarity); Belongs to the glycosyl hydrolase 27 family. | 0.653 |
Glb1 | Fuca1 | ENSRNOP00000013632 | ENSRNOP00000012455 | Beta-galactosidase. | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | 0.825 |
Glb1 | Hexa | ENSRNOP00000013632 | ENSRNOP00000013747 | Beta-galactosidase. | Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.948 |
Glb1 | Hexb | ENSRNOP00000013632 | ENSRNOP00000044480 | Beta-galactosidase. | Beta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.517 |
Glb1 | Naga | ENSRNOP00000013632 | ENSRNOP00000060590 | Beta-galactosidase. | Alpha-N-acetylgalactosaminidase; Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids (By similarity); Belongs to the glycosyl hydrolase 27 family. | 0.697 |
Glb1 | Neu1 | ENSRNOP00000013632 | ENSRNOP00000050614 | Beta-galactosidase. | Sialidase-1; Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage. | 0.958 |
Gm2a | Cyb5d2 | ENSRNOP00000071876 | ENSRNOP00000038452 | GM2 ganglioside activator protein. | Neuferricin; Heme-binding protein which promotes neuronal but not astrocyte differentiation; Belongs to the cytochrome b5 family. MAPR subfamily. | 0.685 |
Gm2a | Hexa | ENSRNOP00000071876 | ENSRNOP00000013747 | GM2 ganglioside activator protein. | Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.917 |
Gm2a | Hexb | ENSRNOP00000071876 | ENSRNOP00000044480 | GM2 ganglioside activator protein. | Beta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.886 |
Hal | Hexa | ENSRNOP00000006971 | ENSRNOP00000013747 | Histidine ammonia-lyase; Belongs to the PAL/histidase family. | Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.550 |